8 / 10 Guest Rating

Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's

Name: Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's
Address: 1517 16th St Sw Rochester, MN 55902, Rochester, us
Rating: 8

1517 16th St Sw Rochester, MN 55902, Rochester, us

Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's - main view

Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's view 2

Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's view 3

Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's view 4

Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's view 5

from US$103 / night

About the Property

Convenient Location in Rochester
Located just 3.6 km from the iconic Plummer Building, the Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's offers a perfect blend of comfort and convenience for your stay in Rochester.

Luxurious Amenities
Indulge in the hotel's spa and wellness centre, complete with an indoor pool, fitness centre, and hot tub. Unwind in the shared lounge or grab a snack at the in-house snack bar. Stay connected with free WiFi and take advantage of the business area for all your work needs.

Exceptional Services
Enjoy a meal at the on-site restaurant, grab a drink at the bar, and benefit from the 24-hour front desk and ATM services. With non-smoking rooms and a range of facilities, including the proximity to Mayo Civic Center and Rochester International Airport, your stay is bound to be seamless.

Book your stay at Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's now for an unforgettable experience.

Facilities & Amenities

Fitness facilities

WiFi available

Free WiFi

Parking

Free Parking

Non-smoking rooms

Air conditioning

Fitness center

Swimming pool

24-hour front desk

Important Information

Check-in & Out

Check-in

Check-out11:00 AM

Property Notes

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. Please inform of your expected arrival time in advance. You can use the Special Requests box when booking, or contact the property directly using the contact details in your confirmation. A deposit may be required at the property.

Check Room Availability

Check-in

Check-out

Guests

1 night · 2 adults

Available Rooms

27 rates found

King Room with Single Sofa Bed - Photo 1

King Room with Single Sofa Bed - Photo 2

King Room with Single Sofa Bed - Photo 3

1/4

King Room with Single Sofa Bed

The triple room provides a tea and coffee maker. The unit offers 2 beds.

23 sqm

Sleeps 3

1 Extra-large double bed (Super-king size) (181-210 cm wide)

1 Sofa bed (Variable Size)

Amenities

Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) availableSingle-room air conditioning for guest accommodation

Room Option

Board / Meal

Price for 1 night

1 King Bed, Nonsmoking, Sofabed, Bath And Shower

Non-refundable

Room Only

20% OFF$128.96

$103.17

Includes taxes & fees

1 King Bed, Non-Smoking, Sofabed for One Person, Work Desk, Microwave and Refrigerator, Bath and Shower

Non-refundable

Breakfast Included

20% OFF$131.04

$104.83

Includes taxes & fees

Queen Room with Two Queen Beds and Work Desk - Photo 1

Queen Room with Two Queen Beds and Work Desk - Photo 2

Queen Room with Two Queen Beds and Work Desk - Photo 3

1/4

Queen Room with Two Queen Beds and Work Desk

The quadruple room features a tea and coffee maker. The unit has 2 beds.

23 sqm

Sleeps 4

2 Queen bed (151-180 cm wide)

Amenities

Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) available

Room Option

Board / Meal

Price for 1 night

Queen Room with Two Queen Beds and Work Desk

Non-refundable

Room Only

20% OFF$138.36

$110.69

Includes taxes & fees

Queen Room with Two Queen Beds and Word Desk - Pool View - Photo 1

Queen Room with Two Queen Beds and Word Desk - Pool View - Photo 2

Queen Room with Two Queen Beds and Word Desk - Pool View - Photo 3

1/4

Queen Room with Two Queen Beds and Word Desk - Pool View

The quadruple room offers a tea and coffee maker. The unit has 2 beds.

23 sqm

Sleeps 4

2 Queen bed (151-180 cm wide)

Amenities

Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) available

Room Option

Board / Meal

Price for 1 night

2 Queen Beds, Nonsmoking, Pool View, Chair With Ottoman, Bath And Shower

Non-refundable

Room Only

20% OFF$128.96

$103.17

Includes taxes & fees

2 Queen Beds, Non-Smoking, Pool View, Chair with Ottoman, Work Desk, Microwave and Refrigerator, Bath and Shower

Non-refundable

Breakfast Included

20% OFF$131.04

$104.83

Includes taxes & fees

Queen Room with Two Queen Beds and Bath Tub - Disability Access - Photo 1

Queen Room with Two Queen Beds and Bath Tub - Disability Access - Photo 2

Queen Room with Two Queen Beds and Bath Tub - Disability Access - Photo 3

1/4

Queen Room with Two Queen Beds and Bath Tub - Disability Access

The quadruple room offers a tea and coffee maker. The unit has 2 beds.

23 sqm

Sleeps 4

2 Queen bed (151-180 cm wide)

Amenities

Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) availableSingle-room air conditioning for guest accommodation

Room Option

Board / Meal

Price for 1 night

ROOM, 2 QUEEN BEDS, ACCESSIBLE

Non-refundable

Breakfast Included

20% OFF$156.19

$124.95

Includes taxes & fees

Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower - Photo 1

Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower - Photo 2

Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower - Photo 3

Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower - Photo 4

1/5

Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower

The quadruple room offers a tea and coffee maker. The unit offers 2 beds.

23 sqm

Sleeps 4

2 Queen bed (151-180 cm wide)

Amenities

Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) availableSingle-room air conditioning for guest accommodation

Room Option

Board / Meal

Price for 1 night

Accessibility - 2 Queens, Roll-in Shower, Chair With Ottoman, Nonsmoking

Non-refundable

Room Only

20% OFF$151.73

$121.38

Includes taxes & fees

Accessible - 2 Queen, Mobility Accessible, Roll In Shower, Chair With Ottoman

Non-refundable

Breakfast Included

20% OFF$157.25

$125.8

Includes taxes & fees

Large Queen Room With Two Queen Beds - Photo 1

Large Queen Room With Two Queen Beds - Photo 2

Large Queen Room With Two Queen Beds - Photo 3

Large Queen Room With Two Queen Beds - Photo 4

1/5

Large Queen Room With Two Queen Beds

The unit offers 2 beds.

23 m2

Sleeps 4

2 Large bed (151-180 cm wide)

Amenities

Single-room air conditioning for guest accommodation

Room Option

Board / Meal

Price for 1 night

2 Queen Beds, Nonsmoking, Chair With Ottoman, Bath And Shower

Non-refundable

Room Only

20% OFF$128.96

$103.17

Includes taxes & fees

2 Queen Beds, Non-Smoking, Chair with Ottoman, Work Desk, Microwave and Refrigerator, Bath and Shower

Non-refundable

Breakfast Included

20% OFF$131.04

$104.83

Includes taxes & fees

King Room with Single Sofa Bed and Pool View - Photo 1

King Room with Single Sofa Bed and Pool View - Photo 2

King Room with Single Sofa Bed and Pool View - Photo 3

King Room with Single Sofa Bed and Pool View - Photo 4

1/5

King Room with Single Sofa Bed and Pool View

The triple room features a tea and coffee maker. The unit has 2 beds.

23 sqm

Sleeps 3

1 Extra-large double bed (Super-king size) (181-210 cm wide)

1 Sofa bed (Variable Size)

Amenities

Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) available

Room Option

Board / Meal

Price for 1 night

1 King Bed, Nonsmoking, Sofabed, Pool View, Bath And Shower

Non-refundable

Room Only

20% OFF$151.73

$121.38

Includes taxes & fees

ROOM, KING BED, POOL VIEW, BATH AND SHOWER, SOFA

Non-refundable

Breakfast Included

20% OFF$156.19

$124.95

Includes taxes & fees

King Room with Mobility Accessible Roll-In Shower - Photo 1

King Room with Mobility Accessible Roll-In Shower - Photo 2

King Room with Mobility Accessible Roll-In Shower - Photo 3

King Room with Mobility Accessible Roll-In Shower - Photo 4

1/5

King Room with Mobility Accessible Roll-In Shower

The double room features a tea and coffee maker. The unit has 1 bed.

23 sqm

Sleeps 2

1 Extra-large double bed (Super-king size) (181-210 cm wide)

Amenities

Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) availableSingle-room air conditioning for guest accommodation

Room Option

Board / Meal

Price for 1 night

Accessibility - 1 King, Roll-in Shower, Chair With Ottoman, Nonsmoking

Non-refundable

Room Only

20% OFF$170.67

$136.54

Includes taxes & fees

Accessible-1 King, Mobility Accessible, Roll in Shower, Chair with Ottoman, Microwave and Refrigerator, Non-Smoking

Non-refundable

Breakfast Included

20% OFF$173.41

$138.73

Includes taxes & fees

1/6

Executive King Room

The triple room features a tea and coffee maker. The unit has 2 beds.

23 sqm

Sleeps 3

1 Extra-large double bed (Super-king size) (181-210 cm wide)

1 Sofa bed (Variable Size)

Amenities

Coffee/tea makerHair dryerRefrigeratorDeskMicrowaveInterconnected room(s) available

Room Option

Board / Meal

Price for 1 night

EXECUTIVE, KING BED, SOFA

Non-refundable

Breakfast Included

20% OFF$169.89

$135.91

Includes taxes & fees

Executive King Room with Fireplace - Photo 1

Executive King Room with Fireplace - Photo 2

Executive King Room with Fireplace - Photo 3

Executive King Room with Fireplace - Photo 4

1/5

Executive King Room with Fireplace

The fireplace is the standout feature of this triple room. The triple room features a tea and coffee maker. The unit has 2 beds.

23 sqm

Sleeps 3

1 Extra-large double bed (Super-king size) (181-210 cm wide)

1 Sofa bed (Variable Size)

Amenities

Coffee/tea makerHair dryerRefrigeratorMicrowaveFireplaceInterconnected room(s) available

Room Option

Board / Meal

Price for 1 night

Executive King Room with Sofabed and Fireplace

Non-refundable

Breakfast Included

20% OFF$178.16

$142.53

Includes taxes & fees

1/5

Executive Queen Room

The quadruple room features a tea and coffee maker. The unit has 2 beds.

23 sqm

Sleeps 4

2 Queen bed (151-180 cm wide)

Amenities

Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) availableToilet paper

Room Option

Board / Meal

Price for 1 night

Executive Queen Room

Non-refundable

Room Only

20% OFF$172.95

$138.36

Includes taxes & fees

Executive King Room - Poolside - Photo 1

Executive King Room - Poolside - Photo 2

Executive King Room - Poolside - Photo 3

Executive King Room - Poolside - Photo 4

1/5

Executive King Room - Poolside

Guests will have a special experience as the triple room provides a spa bath. The triple room features a tea and coffee maker. The unit offers 2 beds.

23 sqm

Sleeps 3

1 Extra-large double bed (Super-king size) (181-210 cm wide)

1 Sofa bed (Variable Size)

Amenities

Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) availableToilet paper

Room Option

Board / Meal

Price for 1 night

1 King Bed, Nonsmoking, Executive Room, Sofabed, Jetted Tub, Pool View

Non-refundable

Room Only

20% OFF$171.69

$137.35

Includes taxes & fees

Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) - Photo 1

Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) - Photo 2

Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) - Photo 3

Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) - Photo 4

1/5

Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room)

2 Queen BedsSoundproofed roomInternet - Free WiFi Entertainment - Premium channels Food & Drink - Mini-fridge, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Iron/ironing board, phone, and electrical adapters/chargers; rollaway beds (surcharge) available on requestComfort - Climate-controlled air conditioning and daily housekeepingNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 4

2 Queen Bed (150-160 cm wide)

Amenities

Coffee/tea makerTVTelephoneHair dryerRefrigeratorMicrowave

Room Option

Board / Meal

Price for 1 night

2 Queen Beds, Nonsmoking, Executive Room, Living Room, Bath And Shower

Non-refundable

Room Only

20% OFF$151.73

$121.38

Includes taxes & fees

EXECUTIVE, 2 QUEEN BEDS, BATH AND SHOWER, LIVING AREA

Non-refundable

Breakfast Included

20% OFF$156.19

$124.95

Includes taxes & fees

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) - Photo 1

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) - Photo 2

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) - Photo 3

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) - Photo 4

1/5

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)

Sleeps 4

2 Queen Bed (150-160 cm wide)

Amenities

Coffee/tea makerTVTelephoneHair dryerRefrigeratorMicrowave

Room Option

Board / Meal

Price for 1 night

Executive Two Queen Room with Pool View

Non-refundable

Breakfast Included

20% OFF$178.16

$142.53

Includes taxes & fees

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 1

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 2

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 3

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 4

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 5

1/6

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room)

Sleeps 4

2 Queen Bed (150-160 cm wide)

Amenities

Coffee/tea makerTVTelephoneHair dryerRefrigeratorMicrowave

Room Option

Board / Meal

Price for 1 night

2 Queen Beds, Non-Smoking, Executive Room, Living Room, Wet Bar, Microwave And Refrigerator, Bath And Shower, Full Breakfast

Non-refundable

Room Only

20% OFF$161.08

$128.86

Includes taxes & fees

EXECUTIVE, 2 QUEEN BEDS, POOL VIEW, BATH AND SHOWER, LIVING AREA

Non-refundable

Breakfast Included

20% OFF$169.89

$135.91

Includes taxes & fees

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 1

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 2

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 3

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 4

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 5

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 6

1/7

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed)

1 King BedSoundproofed roomInternet - Free WiFi Entertainment - Premium channels Food & Drink - Mini-fridge, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Iron/ironing board, phone, and electrical adapters/chargers; rollaway beds (surcharge) available on requestComfort - Climate-controlled air conditioning and daily housekeepingNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 3

1 King bed (151-180 cm wide)

Amenities

Coffee/tea makerTVTelephoneHair dryerRefrigeratorMicrowave

Room Option

Board / Meal

Price for 1 night

1 King Bed, Nonsmoking, Executive Room, Sofabed, Fireplace, Shower Only

Non-refundable

Room Only

20% OFF$165.03

$132.02

Includes taxes & fees

1 King Bed, Non-Smoking, Executive Room, Sofabed For One Person

Non-refundable

Breakfast Included

20% OFF$171.04

$136.83

Includes taxes & fees

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 1

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 2

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 3

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 4

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 5

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 6

1/7

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed)

Sleeps 5

2 Queen Bed (150-160 cm wide)

Amenities

Coffee/tea makerTVTelephoneHair dryerRefrigeratorMicrowave

Room Option

Board / Meal

Price for 1 night

2 Queen Beds, Non-Smoking, Executive Room, Pool View, Living Room, Microwave And Refrigerator, Bath And Shower, Full Breakfast

Non-refundable

Room Only

20% OFF$175.59

$140.47

Includes taxes & fees

Executive Room, 1 King Bed, Jetted Tub, Poolside (with Single Sofabed) - Photo 1

Executive Room, 1 King Bed, Jetted Tub, Poolside (with Single Sofabed) - Photo 2

Executive Room, 1 King Bed, Jetted Tub, Poolside (with Single Sofabed) - Photo 3

Executive Room, 1 King Bed, Jetted Tub, Poolside (with Single Sofabed) - Photo 4

1/5

Executive Room, 1 King Bed, Jetted Tub, Poolside (with Single Sofabed)

Sleeps 3

1 King bed (151-180 cm wide)

Amenities

Coffee/tea makerTVTelephoneHair dryerMicrowavePrivate bathroom

Room Option

Board / Meal

Price for 1 night

EXECUTIVE, KING BED, POOL VIEW, SOFA, JETTED TUB

Non-refundable

Leannea

Verified booking

partner

Standard Room

Stayed in Sep 22, 2025

"Exceptional"

Exceptional

10.0

We have been up here numerous times for my appts at Mayo Clinic and we always stay at this hotel. Staff here are so helpful and friendly. I can’t say a single bad thing about this place or the staff. Highly recommend you won’t be disappointed. Clean, safe, quiet. I travel with my husband and we both enjoy this place. Definitely returning here.

Helpful?

Vanessa

Verified booking

family

Standard Room

Stayed in Sep 19, 2025

"Good"

Good

2.0

Room key didn't work 3x. Lost a family member to cancer at Mayo so we arrived around 1:30am. One younger kid working, no one else to help. Room dirty but we were exhausted. This room was double the cost of so many others so we expect more. Sink plugged, no water pressure in shower and tub not cleaned. Carpet sticky. Told by front desk in morning the mgr would call. Nothing yet. Told by kid that evening they would talk to us that morning, nope - not available. No comps, no help, just dumbfounded look after our horrible situation we had just encountered after not sleeping for 3 days. We stayed prior at Spark and it was WONDERFUL. Go to Spark people! This place, you can't call me back and make it right, don't care...you are in an area where people need accommodations due to difficult situations (Mayo) BE BETTER. You didn't care at all.

Helpful?

pat

Verified booking

couple

Standard Room

Stayed in Sep 18, 2025

"Served it's purpose, without problems...."

Very Good

7.0

Average breakfast. Decent selection

Hot tub opperation

Helpful?

Gregory

Verified booking

family

Standard Room

Stayed in Sep 18, 2025

"Exceptional"

Exceptional

10.0

Convenience

Helpful?

Doris

Verified booking

couple

Standard Room

Stayed in Sep 18, 2025

"Comfortable room"

Good

6.0

Hot Tub not working

Helpful?

7 8

10 10

Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's

About the Property

Facilities & Amenities

Important Information

Check-in & Out

Property Notes

Check Room Availability

Available Rooms

King Room with Single Sofa Bed

Amenities

Queen Room with Two Queen Beds and Work Desk

Amenities

Queen Room with Two Queen Beds and Word Desk - Pool View

Amenities

Queen Room with Two Queen Beds and Bath Tub - Disability Access

Amenities

Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower

Amenities

Large Queen Room With Two Queen Beds

Amenities

King Room with Single Sofa Bed and Pool View

Amenities

King Room with Mobility Accessible Roll-In Shower

Amenities

Executive King Room

Amenities

Executive King Room with Fireplace

Amenities

Executive Queen Room

Amenities

Executive King Room - Poolside

Amenities

Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room)

Amenities

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)

Amenities

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room)

Amenities

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed)

Amenities

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed)

Amenities

Executive Room, 1 King Bed, Jetted Tub, Poolside (with Single Sofabed)

Amenities

Guest Reviews

Categories

Select topics to read reviews

"It’s a Best Western"

"Exceptional"

"Clean, comfortable, adequate."

"Exceptional"

"Exceptional"

"Exceptional"

"Good"

"Served it's purpose, without problems...."

"Exceptional"

"Comfortable room"