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9 / 10 Guest Rating

Hotel Museo Spa Casa Santo Domingo

Tercera Calle Oriente 28 A, Antigua Guatemala, gt

Hotel Museo Spa Casa Santo Domingo - main view

About the Property

Artistic Rooms and SPA Living Concept

Experience a unique stay in our Hotel-Museum-Spa, where each of the 132 rooms is a work of art itself. Enjoy the special SPA Living concept in 26 rooms, adorned with local artistic masterpieces and intricate weavings. Contact us directly for personalized room requests to make your stay truly exceptional.

Gastronomic Delights at El Refectorio

Indulge in a culinary journey at El Refectorio, where Chef Mario Enrique Campollo crafts elegant international dishes with a Guatemalan twist. Explore the ever-changing weekend specials and don't miss the exquisite Sunday brunch. Immerse yourself in the rich flavors of Guatemala with our weekend buffet of traditional afternoon snacks.

Wellness Oasis and Cultural Exploration

Relax and rejuvenate in our world-class spa facilities, offering a range of treatments to restore balance in body and mind. Unwind in indoor/outdoor areas, pools, jacuzzis, and saunas, or book a room with direct spa access for an intimate experience. Explore the cultural treasures within our hotel, including six museums and two art galleries, providing a glimpse into Guatemala's rich heritage.

Book now to embark on a journey of art, gastronomy, wellness, and culture at our enchanting Hotel-Museum-Spa.

Facilities & Amenities

Fitness facilities
WiFi available
Free WiFi
Parking
Free Parking
Non-smoking rooms
Air conditioning
Fitness center
Swimming pool
24-hour front desk

Important Information

Check-in & Out

Check-in
Check-out12:00 PM

Property Notes

The Sofa bed and the crib have an extra fee. Temporary we offer private transportation from the airport to the Hotel and viceversa with and extra charge. At check in, Client must open credit with the Hotel. Most credit cards are accepted. This credit is independent A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Junior Suite - Photo 1
Junior Suite - Photo 2
Junior Suite - Photo 3
Junior Suite - Photo 4
1/4

Junior Suite

This spacious and elegant suite has a separate lounge area with sofa bed and dining table. It features stylish decor,2 double beds X 1 king-size or 2 double beds and pretty garden views. It has a fireplace and comes with Smart TV, a safe, minibar and private bathroom. Free access Wi-Fi. Please note that the price is based on 2 adults, plus 2 children, or in 2 adults plus a additional guest. This additional guest will have to pay USD 44.80 per night. All Junios Suite Rooms are different.

67 sqm
Sleeps 4
2 Double bed (131-150 cm wide)
Amenities
MinibarSafety deposit boxTVTelephoneAir conditioningHair dryer

Junior Suite (All rooms are different) (2 adults 2 children)

Non-refundable
Room Only
20% OFF$441.5

$353.2

Includes taxes & fees

Junior Suite (All rooms are different) (2 adults 2 children)

Non-refundable
Breakfast Included
20% OFF$544.21

$435.37

Includes taxes & fees
Superior Suite, Jetted Tub (All rooms are different) - Photo 1
Superior Suite, Jetted Tub (All rooms are different) - Photo 2
Superior Suite, Jetted Tub (All rooms are different) - Photo 3
Superior Suite, Jetted Tub (All rooms are different) - Photo 4
Superior Suite, Jetted Tub (All rooms are different) - Photo 5
1/5

Superior Suite, Jetted Tub (All rooms are different)

2 Double BedsRelax - FireplaceEntertainment - 42-inch Smart TV with premium channelsFood & Drink - Room service (limited) and minibar (fees may apply)Sleep - Premium bedding, a pillow menu, and bed sheets Bathroom - Private bathroom, bathtub or shower (jetted bathtub available in some rooms)Practical - Safe, iron/ironing board, and phone; rollaway beds (surcharge) and cribs (surcharge) available on requestComfort - Air conditioning and daily housekeepingSmoking And Non-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 4
2 Double bed (131-150 cm wide)
Amenities
MinibarSafety deposit boxTVTelephoneAir conditioningHair dryer

Superior Suite Spa Living (All rooms are different)

Non-refundable
Room Only
20% OFF$679.84

$543.87

Includes taxes & fees

Superior Suite Spa Living (All rooms are different)

Non-refundable
Breakfast Included
20% OFF$824.6

$659.68

Includes taxes & fees
Superior Suite, 1 King Bed, Jetted Tub (All rooms are different) - Photo 1
Superior Suite, 1 King Bed, Jetted Tub (All rooms are different) - Photo 2
Superior Suite, 1 King Bed, Jetted Tub (All rooms are different) - Photo 3
Superior Suite, 1 King Bed, Jetted Tub (All rooms are different) - Photo 4
Superior Suite, 1 King Bed, Jetted Tub (All rooms are different) - Photo 5
Superior Suite, 1 King Bed, Jetted Tub (All rooms are different) - Photo 6
1/6

Superior Suite, 1 King Bed, Jetted Tub (All rooms are different)

1 King BedOverlooking the gardenLayout - Bedroom Relax - FireplaceEntertainment - 42-inch Smart TV with premium channelsFood & Drink - Room service (limited) and minibar (fees may apply)Sleep - Premium bedding, a pillow menu, and bed sheets Bathroom - Private bathroom, bathtub or shower (jetted bathtub available in some rooms)Practical - Safe, iron/ironing board, and phone; rollaway beds (surcharge) and cribs (surcharge) available on requestComfort - Air conditioning and daily housekeepingSmoking And Non-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 2
1 King bed (151-180 cm wide)
Amenities
MinibarSafety deposit boxTVTelephoneAir conditioningHair dryer

Superior Suite Jetted Tub (All rooms are different)

Non-refundable
Room Only
20% OFF$632.18

$505.74

Includes taxes & fees

Superior Suite Jetted Tub (All rooms are different)

Non-refundable
Breakfast Included
20% OFF$768.51

$614.81

Includes taxes & fees
Suite (All rooms are different) - Photo 1
Suite (All rooms are different) - Photo 2
Suite (All rooms are different) - Photo 3
Suite (All rooms are different) - Photo 4
Suite (All rooms are different) - Photo 5
1/5

Suite (All rooms are different)

1 Double BedOverlooking the gardenLayout - Bedroom Relax - FireplaceEntertainment - 42-inch Smart TV with premium channelsFood & Drink - Room service (limited) and minibar (fees may apply)Sleep - Premium bedding, a pillow menu, and bed sheets Bathroom - Private bathroom, bathtub or shower, a hair dryer, and towelsPractical - Safe, iron/ironing board, and phone; rollaway beds (surcharge) and cribs (surcharge) available on requestComfort - Air conditioning and daily housekeepingSmoking And Non-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 2
1 Double bed (131-150 cm wide)
Amenities
MinibarSafety deposit boxTVTelephoneAir conditioningHair dryer

Suite (All rooms are different)

Non-refundable
Room Only
20% OFF$632.18

$505.74

Includes taxes & fees

Suite (All rooms are different)

Non-refundable
Breakfast Included
20% OFF$768.51

$614.81

Includes taxes & fees
Executive Suite, 1 King Bed (All rooms are different) - Photo 1
Executive Suite, 1 King Bed (All rooms are different) - Photo 2
Executive Suite, 1 King Bed (All rooms are different) - Photo 3
Executive Suite, 1 King Bed (All rooms are different) - Photo 4
Executive Suite, 1 King Bed (All rooms are different) - Photo 5
1/5

Executive Suite, 1 King Bed (All rooms are different)

1 King BedLayout - Bedroom Relax - FireplaceEntertainment - 42-inch Smart TV with premium channelsFood & Drink - Room service (limited) and minibar (fees may apply)Sleep - Premium bedding, a pillow menu, and bed sheets Bathroom - Private bathroom, bathtub or shower, a hair dryer, and towelsPractical - Safe, iron/ironing board, and phone; rollaway beds (surcharge) and cribs (surcharge) available on requestComfort - Air conditioning and daily housekeepingNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 2
1 King bed (151-180 cm wide)
Amenities
MinibarSafety deposit boxTVTelephoneAir conditioningHair dryer

Executive Suite (All rooms are different)

Non-refundable
Room Only
20% OFF$434.36

$347.49

Includes taxes & fees

Executive Suite (All rooms are different)

Non-refundable
Breakfast Included
20% OFF$535.81

$428.65

Includes taxes & fees
Superior Suite Spa Living (All rooms are different) - Photo 1
Superior Suite Spa Living (All rooms are different) - Photo 2
Superior Suite Spa Living (All rooms are different) - Photo 3
Superior Suite Spa Living (All rooms are different) - Photo 4
Superior Suite Spa Living (All rooms are different) - Photo 5
Superior Suite Spa Living (All rooms are different) - Photo 6
Superior Suite Spa Living (All rooms are different) - Photo 7
1/7

Superior Suite Spa Living (All rooms are different)

1 King BedRelax - FireplaceEntertainment - 42-inch Smart TV with premium channelsFood & Drink - Room service (limited) and minibar (fees may apply)Sleep - Premium bedding, a pillow menu, and bed sheets Bathroom - Private bathroom, bathtub or shower, a hair dryer, and towelsPractical - Safe, iron/ironing board, and phone; rollaway beds (surcharge) and cribs (surcharge) available on requestComfort - Air conditioning and daily housekeepingNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 2
1 King bed (151-180 cm wide)
Amenities
MinibarSafety deposit boxTVTelephoneAir conditioningHair dryer

Superior Suite 1 King Bed Jetted Tub (All rooms are different)

Non-refundable
Room Only
20% OFF$632.18

$505.74

Includes taxes & fees

Superior Suite 1 King Bed Jetted Tub (All rooms are different)

Non-refundable
Breakfast Included
20% OFF$768.51

$614.81

Includes taxes & fees
Deluxe Suite (All rooms are different) - Photo 1
Deluxe Suite (All rooms are different) - Photo 2
Deluxe Suite (All rooms are different) - Photo 3
Deluxe Suite (All rooms are different) - Photo 4
Deluxe Suite (All rooms are different) - Photo 5
1/5

Deluxe Suite (All rooms are different)

1 King BedOverlooking the gardenLayout - Bedroom Relax - Fireplace; in-room massage availableEntertainment - 42-inch Smart TV with premium channelsFood & Drink - Room service (limited) and minibar (fees may apply)Sleep - Pillowtop bed, premium bedding, a pillow menu, and bed sheets Bathroom - Private bathroom, bathtub or shower, bathrobes, and a hair dryerPractical - Safe, iron/ironing board, and phone; rollaway beds (surcharge) and cribs (surcharge) available on requestComfort - Air conditioning and daily housekeepingSmoking And Non-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 2
1 King bed (151-180 cm wide)
Amenities
MinibarSafety deposit boxTVTelephoneAir conditioningHair dryer

Deluxe Suite (All rooms are different)

Non-refundable
Room Only
20% OFF$482

$385.6

Includes taxes & fees

Deluxe Suite (All rooms are different)

Non-refundable
Breakfast Included
20% OFF$591.88

$473.5

Includes taxes & fees
Standard Room (All rooms are different) - Photo 1
Standard Room (All rooms are different) - Photo 2
Standard Room (All rooms are different) - Photo 3
Standard Room (All rooms are different) - Photo 4
Standard Room (All rooms are different) - Photo 5
1/5

Standard Room (All rooms are different)

2 Double Beds204-sq-foot room with garden views Relax - FireplaceEntertainment - 42-inch Smart TV with premium channelsFood & Drink - Room service (limited) and minibar (fees may apply)Sleep - Premium bedding, a pillow menu, and bed sheets Bathroom - Private bathroom, bathtub or shower, a hair dryer, and towelsPractical - Safe, iron/ironing board, and phone; rollaway beds (surcharge) and cribs (surcharge) available on requestComfort - Air conditioning and daily housekeepingSmoking And Non-SmokingConnecting/adjoining rooms can be requested, subject to availability

19 m2
Sleeps 4
2 Double bed (131-150 cm wide)
Amenities
MinibarSafety deposit boxTVTelephoneAir conditioningHair dryer

Standard Room (All rooms are different)

Non-refundable
Room Only
20% OFF$364.04

$291.23

Includes taxes & fees

Standard Room (All rooms are different)

Non-refundable
Breakfast Included
20% OFF$453.08

$362.46

Includes taxes & fees

Guest Reviews

9
Exceptional1995 verified reviews
AI Summary

Guests highly rate the beautiful design and location and frequently praise the exceptional service and amenities.

Categories

Cleanliness8.5
Service9.4
Location9.5
Room Quality7.9
Amenities9.4
Value for Money8.4
Food and Beverage9.5
Overall Experience9.4

Select topics to read reviews

D
DANIELAesES
Verified booking
couple
Standard Room
Stayed in May 16, 2026

"Miedo"

6.0

Las instalaciones son hermosas el personal fue muy amable, la calidad del desayuno fue muy buena

Lamentablemente, la segunda noche, una amiga y yo fuimos solas al bar del Hotel, ordenamos un cóctel cada una, el mismo cóctel por cierto (Moscow Mule) y luego salimos de allí directo a cenar, más o menos 30 minutos después de habernos tomado ese cóctel, nos desmayamos las dos en cuestión de segundos. Claramente nos pusieron algo en el trago. Lo reclamamos al gerente del bar y nos dijo que había revisado todas los vídeos y que todo estaba correcto. Realmente tampoco esperaba que asumieran ninguna responsabilidad. Es la primera vez en mi vida que me pasa esto.

Helpful?
C
ClaudiausUS
Verified booking
couple
Standard Room
Stayed in May 15, 2026

"Very Good"

7.0

Customer service needs improvement.

Not all the staff at reception is friendly . I think if you work in customer service you should be more friendly.

Helpful?
J
JaimecrCR
Verified booking
family_with_children
Standard Room
Stayed in May 15, 2026

"Exceptional"

10.0
Helpful?
V
ValchCH
Verified booking
solo_traveller
Standard Room
Stayed in May 14, 2026

"Exceptional"

10.0

Wow

Helpful?
C
CaterinegtGT
Verified booking
family_with_children
Standard Room
Stayed in May 12, 2026

"Exceptional"

9.0

las instalaciones

todo tiene un costo extra

Helpful?
K
KimAnnetteusUS
Verified booking
couple
Standard Room
Stayed in May 12, 2026

"Great Stay in Antigua"

10.0

Stunning Property!!!! Beautiful large rooms!!!! Amazing spa!!!!! Wonderful staff!!!! Great location!!!!!

Nothing!!!!

Helpful?
S
SebastiancoCO
Verified booking
couple
Standard Room
Stayed in May 11, 2026

"Great for a romantic getaway"

10.0

Architecture, 10/10 breakfast, location, parking.

Breakfast was a bit crowded, thankfully we booked a table previously.

Helpful?
L
lydiagrGR
Verified booking
couple
Standard Room
Stayed in May 10, 2026

"Exceptional"

10.0
Helpful?
A
ANA CLAUDIAbrBR
Verified booking
solo_traveller
Standard Room
Stayed in May 9, 2026

"Best choice in the beautiful Antigua"

10.0

The room that I booked was better than what I imagined, with a gorgeous terrace overlooking the Volcano of Water!!

Some of the decoration elements seemed a little creepy

Helpful?
M
MarianamxMX
Verified booking
solo_traveller
Standard Room
Stayed in May 7, 2026

"Excellent"

8.0

Un lugar estupendo y la atención bien.

Entran a la habitación durante el día (acomodo y disposición de papelería) sin tu consentimiento. Eso es un poco invasivo.

Helpful?
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