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10 / 10 Guest Rating

Hampton Inn & Suites St. Louis/South I-55

4200 Midamerica Lane, St. Louis, Missouri, 63129, St. Louis, US

Hampton Inn & Suites St. Louis/South I-55 - main view

About the Property

Recreational Amenities and Features
Indulge in relaxation at the indoor pool or maintain your fitness routine in the on-site fitness center. Unwind by the cozy fireplace in the lobby or grab a snack from the convenient vending machine.

Complimentary Services and Offerings
Stay connected with free wireless internet access, enjoy a daily buffet breakfast, and make use of complimentary wired internet access. Benefit from amenities such as a business center, express check-in, and free self-parking.

Accommodations and Nearby Attractions
Retreat to one of the 92 guestrooms equipped with modern amenities. Explore nearby landmarks like Barnes Jewish South Campus and Suson Park, with various other attractions just a short drive away.

For a convenient and comfortable stay in St. Louis, book your stay at Hampton Inn & Suites St. Louis/South I-55 today!

Facilities & Amenities

Free breakfast
Fitness facilities
Fireplace in lobby
Free WiFi
24-hour front desk
Luggage storage
Express check-in/check-out
Wheelchair accessible
Elevator
Fitness facilities

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Pool access available from 8 AM to 10 PM.The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation. Contactless check-in and contactless check-out are available.This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Check Room Availability

1 night · 2 adults

Available Rooms

One King Bed, Non-Smoking, Accessible - Photo 1
One King Bed, Non-Smoking, Accessible - Photo 2
One King Bed, Non-Smoking, Accessible - Photo 3
One King Bed, Non-Smoking, Accessible - Photo 4
One King Bed, Non-Smoking, Accessible - Photo 5
One King Bed, Non-Smoking, Accessible - Photo 6
One King Bed, Non-Smoking, Accessible - Photo 7
One King Bed, Non-Smoking, Accessible - Photo 8
1/8

One King Bed, Non-Smoking, Accessible

1 King Bed460 sq feet Internet - Free WiFi and wired internet accessEntertainment - 37-inch LCD TV with cable channels and pay moviesFood & Drink - Refrigerator, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower/tub combination, and hydromassage showerheadPractical - Desk, safe, and free weekday newspaper; cribs (free) available on requestComfort - Climate-controlled air conditioning and daily housekeepingAccessibility - Wheelchair accessibleNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

43 m2
Sleeps 2
1 King bed (151-180 cm wide)
Amenities
Coffee/tea makerSafety deposit boxTVTelephoneHair dryerRefrigerator

1KG MOBILITY/HEARING ACCESS RI SHWR STUDIO NS

Non-refundable
Breakfast Included
20% OFF$237.88

$190.3

Includes taxes & fees

1 KING MOBILITY/HEARING ACCESS W/TUB NONSMOK

Free cancellation
Before Jul 1 (2 days)
Breakfast Included
20% OFF$251.83

$201.46

Includes taxes & fees
Room, 1 King Bed, Non Smoking - Photo 1
Room, 1 King Bed, Non Smoking - Photo 2
1/2

Room, 1 King Bed, Non Smoking

1 King Bed460 sq feet Internet - Free WiFi and wired internet accessEntertainment - 37-inch LCD TV with cable channels and pay moviesFood & Drink - Refrigerator, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Safe, free weekday newspaper, and iron/ironing board; free cribs/infant beds available on requestComfort - Climate-controlled air conditioning and daily housekeepingAccessibility - Closed-captioned TVNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

43 m2
Sleeps 2
Amenities
Coffee/tea makerSafety deposit boxTVTelephoneHair dryerRefrigerator

2 QUEEN BEDS NONSMOKING

Non-refundable
Breakfast Included
20% OFF$223.71

$178.97

Includes taxes & fees

2 Queen Beds Nonsmoking

Free cancellation
Before Jul 1 (2 days)
Breakfast Included
20% OFF$236.83

$189.46

Includes taxes & fees
Studio, Accessible, Non Smoking - Photo 1
Studio, Accessible, Non Smoking - Photo 2
Studio, Accessible, Non Smoking - Photo 3
Studio, Accessible, Non Smoking - Photo 4
Studio, Accessible, Non Smoking - Photo 5
Studio, Accessible, Non Smoking - Photo 6
Studio, Accessible, Non Smoking - Photo 7
Studio, Accessible, Non Smoking - Photo 8
1/8

Studio, Accessible, Non Smoking

1 King Bed460 sq feet Layout - Separate sitting areaInternet - Free WiFi and wired internet accessEntertainment - 37-inch LCD TV with cable channels and pay moviesFood & Drink - Refrigerator, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower, and hydromassage showerheadPractical - Free local calls, double sofa bed, and desk; cribs (free) available on requestComfort - Climate-controlled air conditioning and daily housekeepingAccessibility - Wheelchair accessibleNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

43 m2
Sleeps 3
1 King bed (151-180 cm wide)
Amenities
Coffee/tea makerShowerSafety deposit boxTVTelephoneHair dryer

Mobility Hearing Accessible King Studio with Roll in Shower

Non-refundable
Breakfast Included
20% OFF$246.58

$197.26

Includes taxes & fees
Room - Photo 1
Room - Photo 2
Room - Photo 3
Room - Photo 4
Room - Photo 5
1/5

Room

2 Queen Beds460 sq feet Internet - Free WiFi and wired internet accessEntertainment - 37-inch LCD TV with cable channels and pay moviesFood & Drink - Refrigerator, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower, and hydromassage showerheadPractical - Desk, safe, and free weekday newspaper; cribs (free) available on requestComfort - Climate-controlled air conditioning and daily housekeepingAccessibility - Phone accessibility kitNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

43 m2
Sleeps 4
2 Queen Bed (150-160 cm wide)
Amenities
Coffee/tea makerShowerSafety deposit boxTVTelephoneHair dryer

2 Queen Beds Room, Non-Smoking

Non-refundable
Breakfast Included
20% OFF$231.9

$185.52

Includes taxes & fees

Guest Reviews

10
Exceptional152 verified reviews
AI Summary

Guests highly rate the cleanliness and frequently praise the helpful staff.

Categories

Cleanliness10.0
Service10.0
Location10.0
Room Quality10.0
Amenities10.0
Value for Money10.0
Food and Beverage10.0
Overall Experience10.0

Select topics to read reviews

S
Sherry
Verified booking
Standard Room
Stayed in May 17, 2025

"On the way home!"

10.0

Very nice stay with great service!

Helpful?
M
Mike
Verified booking
family
Standard Room
Stayed in May 16, 2025

"Exceptional"

10.0

Like any other highway hotel it serves purpose, but we do stay here often. We have family in St. Louis and there are hundreds of choices for hotels. We choose this property brcause of the staff they are always friendly helpful and the hotel is always clean.

Helpful?
A
Angie
Verified booking
Standard Room
Stayed in May 12, 2025

"Great stay"

10.0

Convenient, clean and would stay there again if I needed to

Helpful?
S
Studio-SteveSPRINGFIELD, MISSOURI
Verified booking
Family
Standard Room
Stayed in May 2, 2025

"Always the best!"

10.0

My family and I have been to this hotel dozens of time now since they built this hotel. It’s been almost flawless, and in my opinion, the benchmark for which Hilton needs to base ALL their Hampton Inn’s on! The staff is always friendly. The rooms are nicely decorated and very little wear is seen. Bathrooms and bedding are super clean. Breakfast, although a free buffet, is still the best free buffet I’ve experienced at any hotel with free breakfast. I will return again and again! Keep up the good work Hampton Inn managers!!!

Helpful?
E
Eight-ishOMAHA, NEBRASKA
Verified booking
Family
Standard Room
Stayed in May 2, 2025

"Great"

10.0

Welcoming smile at front desk. Very nice stay. Clean and. Easy check in even in a last minute reservation. Over all a very perfect relaxing night that was needed after some long travels. Easy access off hwy, great breakfast and very comfy beds.

Helpful?
R
Richard
Verified booking
Standard Room
Stayed in Apr 20, 2025

"Perfect "

10.0

Great hotel

Helpful?
W
W1749MDstevenf
Verified booking
Family
Standard Room
Stayed in Apr 3, 2025

"Friendly staff, clean rooms, not a resort but very nice."

10.0

The staff was so insanely friendly, with the exception of one crabby worker. Rooms were spotless, renovated and very spacious. The sheets were soft and clean. Breakfast buffet was plentiful with options, but be careful-- my son burned his hand really bad on the waffle iron in the kitchen. I'd avoid those machines, they overheat really bad. The hotel is in walking distance to Popeye's, and we enjoyed the various amenities the hotel had to offer.

Helpful?
F
Franklin
Verified booking
family
Standard Room
Stayed in Mar 31, 2025

"Exceptional"

10.0

Enjoyed our stay and would return.

Helpful?
M
michaelkK8006DGROCKFORD, ILLINOIS
Verified booking
Family
Standard Room
Stayed in Mar 30, 2025

"Standard family stay. High side of C+ stay."

8.0

Check in was easy as always, food breakfast was the typical cheap hotel fair, with no vegan options like the Marriott. The room was clean staff friendly. Still after multiple stays they have few available luggage carts and only one working elevator going on almost two years now. When teenagers and children are allowed to run wild due to permissive parenting getting an elevator and luggage cart can take upwards of 30 min at check in/out.

Helpful?
A
Anthony
Verified booking
partner
Standard Room
Stayed in Mar 30, 2025

"Exceptional"

10.0

Easy check in, fats and efficient!

Helpful?
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