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8 / 10 Guest Rating

Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's

1517 16th St Sw Rochester, MN 55902, Rochester, us

Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's - main view

About the Property

Convenient Location in Rochester
Located just 3.6 km from the iconic Plummer Building, the Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's offers a perfect blend of comfort and convenience for your stay in Rochester.

Luxurious Amenities
Indulge in the hotel's spa and wellness centre, complete with an indoor pool, fitness centre, and hot tub. Unwind in the shared lounge or grab a snack at the in-house snack bar. Stay connected with free WiFi and take advantage of the business area for all your work needs.

Exceptional Services
Enjoy a meal at the on-site restaurant, grab a drink at the bar, and benefit from the 24-hour front desk and ATM services. With non-smoking rooms and a range of facilities, including the proximity to Mayo Civic Center and Rochester International Airport, your stay is bound to be seamless.

Book your stay at Best Western Rochester Hotel Mayo Clinic Area/ St. Mary's now for an unforgettable experience.

Facilities & Amenities

Fitness facilities
WiFi available
Free WiFi
Parking
Free Parking
Non-smoking rooms
Air conditioning
Fitness center
Swimming pool
24-hour front desk

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. Please inform of your expected arrival time in advance. You can use the Special Requests box when booking, or contact the property directly using the contact details in your confirmation. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Queen Room with Two Queen Beds and Work Desk - Photo 1
Queen Room with Two Queen Beds and Work Desk - Photo 2
Queen Room with Two Queen Beds and Work Desk - Photo 3
Queen Room with Two Queen Beds and Work Desk - Photo 4
1/4

Queen Room with Two Queen Beds and Work Desk

The quadruple room features a tea and coffee maker. The unit has 2 beds.

23 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) available

Queen Room with Two Queen Beds and Work Desk

Non-refundable
Room Only
20% OFF$138.36

$110.69

Includes taxes & fees

2 Queen Beds, Non-Smoking, Chair With Ottoman, Work Desk, Microwave And Refrigerator

Non-refundable
Breakfast Included
20% OFF$139.91

$111.93

Includes taxes & fees
Queen Room with Two Queen Beds and Word Desk - Pool View - Photo 1
Queen Room with Two Queen Beds and Word Desk - Pool View - Photo 2
Queen Room with Two Queen Beds and Word Desk - Pool View - Photo 3
Queen Room with Two Queen Beds and Word Desk - Pool View - Photo 4
1/4

Queen Room with Two Queen Beds and Word Desk - Pool View

The quadruple room offers a tea and coffee maker. The unit has 2 beds.

23 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) available

2 Queen Beds, Nonsmoking, Pool View, Chair With Ottoman, Bath And Shower

Non-refundable
Room Only
20% OFF$127

$101.6

Includes taxes & fees

2 Queen Beds, Non-Smoking, Pool View, Chair with Ottoman, Work Desk, Microwave and Refrigerator, Bath and Shower

Non-refundable
Breakfast Included
20% OFF$129.06

$103.25

Includes taxes & fees
Queen Room with Two Queen Beds and Bath Tub - Disability Access - Photo 1
Queen Room with Two Queen Beds and Bath Tub - Disability Access - Photo 2
Queen Room with Two Queen Beds and Bath Tub - Disability Access - Photo 3
Queen Room with Two Queen Beds and Bath Tub - Disability Access - Photo 4
1/4

Queen Room with Two Queen Beds and Bath Tub - Disability Access

The quadruple room offers a tea and coffee maker. The unit has 2 beds.

23 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) availableSingle-room air conditioning for guest accommodation

Accessible - 2 Queen

Non-refundable
Breakfast Included
20% OFF$165.26

$132.21

Includes taxes & fees
Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower - Photo 1
Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower - Photo 2
Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower - Photo 3
Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower - Photo 4
Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower - Photo 5
1/5

Queen Room with Two Queen Beds and Mobility Accessible Roll-In Shower

The quadruple room offers a tea and coffee maker. The unit offers 2 beds.

23 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) availableSingle-room air conditioning for guest accommodation

Accessibility - 2 Queens, Roll-in Shower, Chair With Ottoman, Nonsmoking

Non-refundable
Breakfast Included
20% OFF$182.86

$146.29

Includes taxes & fees
Large Queen Room With Two Queen Beds - Photo 1
Large Queen Room With Two Queen Beds - Photo 2
Large Queen Room With Two Queen Beds - Photo 3
Large Queen Room With Two Queen Beds - Photo 4
Large Queen Room With Two Queen Beds - Photo 5
1/5

Large Queen Room With Two Queen Beds

The unit offers 2 beds.

23 m2
Sleeps 4
2 Large bed (151-180 cm wide)
Amenities
Single-room air conditioning for guest accommodation

2 Queen Beds, Nonsmoking, Chair With Ottoman, Bath And Shower

Non-refundable
Room Only
20% OFF$127

$101.6

Includes taxes & fees

2 Queen Beds, Non-Smoking, Chair with Ottoman, Work Desk, Microwave and Refrigerator, Bath and Shower

Non-refundable
Breakfast Included
20% OFF$129.06

$103.25

Includes taxes & fees
King Room with Single Sofa Bed and Pool View - Photo 1
King Room with Single Sofa Bed and Pool View - Photo 2
King Room with Single Sofa Bed and Pool View - Photo 3
King Room with Single Sofa Bed and Pool View - Photo 4
King Room with Single Sofa Bed and Pool View - Photo 5
1/5

King Room with Single Sofa Bed and Pool View

The triple room features a tea and coffee maker. The unit has 2 beds.

23 sqm
Sleeps 3
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) available

1 King Bed, Nonsmoking, Sofabed, Pool View, Bath And Shower

Non-refundable
Room Only
20% OFF$149.43

$119.54

Includes taxes & fees

ROOM, KING BED, POOL VIEW, BATH AND SHOWER, SOFA

Non-refundable
Breakfast Included
20% OFF$153.85

$123.08

Includes taxes & fees
King Room with Mobility Accessible Roll-In Shower - Photo 1
King Room with Mobility Accessible Roll-In Shower - Photo 2
King Room with Mobility Accessible Roll-In Shower - Photo 3
King Room with Mobility Accessible Roll-In Shower - Photo 4
King Room with Mobility Accessible Roll-In Shower - Photo 5
1/5

King Room with Mobility Accessible Roll-In Shower

The double room features a tea and coffee maker. The unit has 1 bed.

23 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) availableSingle-room air conditioning for guest accommodation

Accessibility - 1 King, Roll-in Shower, Chair With Ottoman, Nonsmoking

Non-refundable
Room Only
20% OFF$168.09

$134.47

Includes taxes & fees

Accessible-1 King, Mobility Accessible, Roll in Shower, Chair with Ottoman, Microwave and Refrigerator, Non-Smoking

Non-refundable
Breakfast Included
20% OFF$170.81

$136.65

Includes taxes & fees
Executive King Room - Photo 1
Executive King Room - Photo 2
Executive King Room - Photo 3
Executive King Room - Photo 4
Executive King Room - Photo 5
Executive King Room - Photo 6
1/6

Executive King Room

The triple room features a tea and coffee maker. The unit has 2 beds.

23 sqm
Sleeps 3
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerHair dryerRefrigeratorDeskMicrowaveInterconnected room(s) available

EXECUTIVE, KING BED, SOFA

Non-refundable
Breakfast Included
20% OFF$153.85

$123.08

Includes taxes & fees
Executive King Room with Fireplace - Photo 1
Executive King Room with Fireplace - Photo 2
Executive King Room with Fireplace - Photo 3
Executive King Room with Fireplace - Photo 4
Executive King Room with Fireplace - Photo 5
1/5

Executive King Room with Fireplace

The fireplace is the standout feature of this triple room. The triple room features a tea and coffee maker. The unit has 2 beds.

23 sqm
Sleeps 3
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerHair dryerRefrigeratorMicrowaveFireplaceInterconnected room(s) available

Executive King Room with Sofabed and Fireplace

Non-refundable
Breakfast Included
20% OFF$175.49

$140.39

Includes taxes & fees
Executive Queen Room - Photo 1
Executive Queen Room - Photo 2
Executive Queen Room - Photo 3
Executive Queen Room - Photo 4
Executive Queen Room - Photo 5
1/5

Executive Queen Room

The quadruple room features a tea and coffee maker. The unit has 2 beds.

23 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerHair dryerRefrigeratorMicrowaveInterconnected room(s) availableToilet paper

Executive Queen Room

Non-refundable
Room Only
20% OFF$172.95

$138.36

Includes taxes & fees
Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) - Photo 1
Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) - Photo 2
Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) - Photo 3
Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) - Photo 4
Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room) - Photo 5
1/5

Executive Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Living Room)

2 Queen BedsSoundproofed roomInternet - Free WiFi Entertainment - Premium channels Food & Drink - Mini-fridge, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Iron/ironing board, phone, and electrical adapters/chargers; rollaway beds (surcharge) available on requestComfort - Climate-controlled air conditioning and daily housekeepingNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 4
2 Queen Bed (150-160 cm wide)
Amenities
Coffee/tea makerTVTelephoneHair dryerRefrigeratorMicrowave

2 Queen Beds, Nonsmoking, Executive Room, Living Room, Bath And Shower

Non-refundable
Room Only
20% OFF$149.43

$119.54

Includes taxes & fees

EXECUTIVE, 2 QUEEN BEDS, BATH AND SHOWER, LIVING AREA

Non-refundable
Breakfast Included
20% OFF$153.85

$123.08

Includes taxes & fees
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) - Photo 1
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) - Photo 2
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) - Photo 3
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) - Photo 4
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) - Photo 5
1/5

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)

2 Queen BedsSoundproofed roomInternet - Free WiFi Entertainment - Premium channels Food & Drink - Mini-fridge, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Iron/ironing board, phone, and electrical adapters/chargers; rollaway beds (surcharge) available on requestComfort - Climate-controlled air conditioning and daily housekeepingNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 4
2 Queen Bed (150-160 cm wide)
Amenities
Coffee/tea makerTVTelephoneHair dryerRefrigeratorMicrowave

Executive Two Queen Room with Pool View

Non-refundable
Breakfast Included
20% OFF$175.49

$140.39

Includes taxes & fees
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 1
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 2
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 3
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 4
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 5
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room) - Photo 6
1/6

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (Living Room)

2 Queen BedsSoundproofed roomInternet - Free WiFi Entertainment - Premium channels Food & Drink - Mini-fridge, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Iron/ironing board, phone, and electrical adapters/chargers; rollaway beds (surcharge) available on requestComfort - Climate-controlled air conditioning and daily housekeepingNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 4
2 Queen Bed (150-160 cm wide)
Amenities
Coffee/tea makerTVTelephoneHair dryerRefrigeratorMicrowave

2 Queen Beds, Non-Smoking, Executive Room, Living Room, Wet Bar, Microwave And Refrigerator, Bath And Shower, Full Breakfast

Non-refundable
Room Only
20% OFF$158.65

$126.92

Includes taxes & fees

2 Queen Beds Non-Smoking Executive Room Living Room Wet Bar Microwave And Refrigerator Bath And Show

Non-refundable
Breakfast Included
20% OFF$159.99

$127.99

Includes taxes & fees
Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 1
Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 2
Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 3
Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 4
Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 5
Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 6
Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed) - Photo 7
1/7

Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (Shower Only;with Single Sofabed)

1 King BedSoundproofed roomInternet - Free WiFi Entertainment - Premium channels Food & Drink - Mini-fridge, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Iron/ironing board, phone, and electrical adapters/chargers; rollaway beds (surcharge) available on requestComfort - Climate-controlled air conditioning and daily housekeepingNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 3
1 King bed (151-180 cm wide)
Amenities
Coffee/tea makerTVTelephoneHair dryerRefrigeratorMicrowave

1 King Bed, Nonsmoking, Executive Room, Sofabed, Shower Only

Non-refundable
Room Only
20% OFF$149.43

$119.54

Includes taxes & fees

1 King Bed, Non-Smoking, Executive Room, Sofabed For One Person

Non-refundable
Breakfast Included
20% OFF$155.44

$124.35

Includes taxes & fees
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 1
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 2
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 3
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 4
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 5
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 6
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed) - Photo 7
1/7

Executive Room, 2 Queen Beds, Refrigerator & Microwave, Poolside (with Single Sofabed)

2 Queen BedsSoundproofed roomInternet - Free WiFi Entertainment - Premium channels Food & Drink - Mini-fridge, microwave, and coffee/tea makerSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Iron/ironing board, phone, and electrical adapters/chargers; rollaway beds (surcharge) available on requestComfort - Climate-controlled air conditioning and daily housekeepingNon-SmokingConnecting/adjoining rooms can be requested, subject to availability

Sleeps 5
2 Queen Bed (150-160 cm wide)
Amenities
Coffee/tea makerTVTelephoneHair dryerRefrigeratorMicrowave

2 Queen Beds, Non-Smoking, Executive Room, Pool View, Living Room, Microwave And Refrigerator, Bath And Shower, Full Breakfast

Non-refundable
Room Only
20% OFF$172.95

$138.36

Includes taxes & fees

Guest Reviews

8
Excellent775 verified reviews
AI Summary

Guests highly rate the good location and frequently praise the great breakfast.

Categories

Cleanliness7.0
Service8.0
Location9.0
Room Quality7.5
Amenities7.5
Value for Money8.0
Food and Beverage9.0
Overall Experience8.0

Select topics to read reviews

S
shelleyusUS
Verified booking
family_with_children
Standard Room
Stayed in Jun 23, 2026

"Great visit and great value - would definitely stay there again."

8.0

The hotel was close to parks and restaurants and a very pleasant place to stay. We chose a room away from the pool area so it was also very quiet. The staff was wonderful. We never used the pool but it looked like a lot of fun and has a slide - seems like a great place for families.

The breakfast seemed good but get there early - they didn't really restock food as it got close to the end of breakfast.

Helpful?
P
PatriciausUS
Verified booking
extended_group
Standard Room
Stayed in Jun 23, 2026

"Very Good"

7.0

Close to our venue.

Didn’t make up beds during our 2 night stay.

Helpful?
A
AmyusUS
Verified booking
couple
Standard Room
Stayed in Jun 18, 2026

"Exceptional"

10.0
Helpful?
G
GailusUS
Verified booking
couple
Standard Room
Stayed in Jun 13, 2026

"Exceptional"

10.0

Great location great staff clean very nice

Helpful?
A
AlexisusUS
Verified booking
solo_traveller
Standard Room
Stayed in Jun 11, 2026

"Exceptional"

10.0

I liked that there was a Waterpark there that was awesome

N/A

Helpful?
S
SharonusUS
Verified booking
family_with_children
Standard Room
Stayed in Jun 10, 2026

"Good"

6.0

Was okay place for a one night stay.

Elevator not easy to location of room.

Helpful?
D
DanielusUS
Verified booking
solo_traveller
Standard Room
Stayed in Jun 7, 2026

"Exceptional"

9.0
Helpful?
T
TamiusUS
Verified booking
solo_traveller
Standard Room
Stayed in Jun 6, 2026

"Exceptional"

9.0
Helpful?
T
ThomasusUS
Verified booking
solo_traveller
Standard Room
Stayed in May 25, 2026

"Very Good"

7.0
Helpful?
T
TrinausUS
Verified booking
family_with_children
Standard Room
Stayed in May 21, 2026

"Overall awesome!"

10.0

Everyone was very helpful, clean rooms, good breakfast.

The pool was down for my children

Helpful?