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8.6 / 10 Guest Rating

Holiday Inn Express Rochester South - Mayo Area by IHG

4141 Maine Avenue SE, Rochester, us

Holiday Inn Express Rochester South - Mayo Area by IHG - main view

About the Property

Spacious Suites with Free WiFi and Shuttle Service
The Comfort Suites Rochester offers spacious suites with free WiFi and flat-screen cable TV. Each suite includes a large work desk, sofa bed, refrigerator, microwave, and coffee maker. A free shuttle to the Rochester Mayo Clinic is available, just 5 miles away.

Indoor Pool, Hot Tub, and Fitness Room
Guests can relax in the indoor pool and hot tub or stay active in the on-site fitness room. The hotel also provides a business center with free WiFi in the lobby for guests' convenience.

Convenient Amenities and Nearby Attractions
Enjoy a daily continental breakfast and a free weekday newspaper during your stay. With Willow Creek Golf Course just 2 miles away, shopping at Apache Mall 4.8 miles away, and easy access to Rochester International Airport, the Comfort Suites Rochester is the perfect choice for your visit.

Facilities & Amenities

WiFi available
Free WiFi
Parking
Free Parking
Non-smoking rooms
Air conditioning
Fitness center
Swimming pool
24-hour front desk
Business center

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Upon check-in, photo identification and credit card is required. All special requests are subject to availability upon check-in. Special requests cannot be guaranteed and may incur additional charges. We are your home away from home, whether traveling for work, pleasure or medical treatment. We offer spacious accommodations and friendly service to all of our guests, as well as special discount rates for patients and family attending the Mayo Clinic. Stay in comfortable guest rooms with premium bedding, a microwave and refrigerator, a work desk and a flat-screen TV. All rooms also have a coffee maker and a USB ports. Guests can start their morning with free hot breakfast and a free weekday newspaper, and enjoy free Wi-Fi anytime. The fitness center and heated indoor pool and hot tub are a great way to relax after a long day. We’re located mere minutes from the Mayo Clinic, so whether you’re visiting the clinic for work or treatment, or visiting a family member or friend, you won't need to commute far. We’re also close to St. Mary’s Hospital and IBM Rochester, as well as Rochester International Airport. Likewise, we have shuttle services to the Mayo Clinic & St. Mary's Hospital. Furthermore, we do not provide Airport Shuttle or local shuttle services to other places. To blow off some steam, hit the nearby Skyline Raceway or head into downtown Rochester for some local dining or shopping. Business travelers will appreciate our business center with a copy and fax machine, and can rent out our meeting rooms for meetings or other events. Laundry and a valet cleaning service are available for guests, as well as a picnic area and on-site coffee shop and sundry shop.Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Suite with Two Queen Beds - Photo 1

Suite with Two Queen Beds

This air-conditioned suite is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 3 beds.

0
Sleeps 6
1 Sofa bed (Variable Size)
2 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

2 Queen Bed Suite

Non-refundable
Breakfast Included
20% OFF$153.66

$122.93

Includes taxes & fees
King Suite - Photo 1

King Suite

This air-conditioned suite is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

King Suite

Non-refundable
Breakfast Included
20% OFF$146.93

$117.54

Includes taxes & fees
Standard King Room with Lake View - Photo 1
Standard King Room with Lake View - Photo 2
Standard King Room with Lake View - Photo 3
Standard King Room with Lake View - Photo 4
Standard King Room with Lake View - Photo 5
Standard King Room with Lake View - Photo 6
Standard King Room with Lake View - Photo 7
Standard King Room with Lake View - Photo 8
Standard King Room with Lake View - Photo 9
Standard King Room with Lake View - Photo 10
1/10

Standard King Room with Lake View

This air-conditioned double room is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

Standard King Room With Lake View

Non-refundable
Breakfast Included
20% OFF$173.89

$139.11

Includes taxes & fees
Standard Room - Photo 1
Standard Room - Photo 2
Standard Room - Photo 3
Standard Room - Photo 4
Standard Room - Photo 5
Standard Room - Photo 6
Standard Room - Photo 7
Standard Room - Photo 8
1/8

Standard Room

Offering free toiletries, this double room includes a private bathroom with a hairdryer. The air-conditioned double room offers a flat-screen TV with cable channels, a tea and coffee maker, a wardrobe, a sofa as well as lake views.

0
Sleeps 2
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

Standard Room

Non-refundable
Breakfast Included
20% OFF$153.66

$122.93

Includes taxes & fees
King Suite with Jetted Tub - Photo 1
King Suite with Jetted Tub - Photo 2
1/2

King Suite with Jetted Tub

This air-conditioned suite includes a flat-screen TV with cable channels and a private bathroom. The unit offers 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningRefrigeratorDesk

King Suite With Jetted Tub

Non-refundable
Breakfast Included
20% OFF$173.89

$139.11

Includes taxes & fees
King Suite with Tub - Mobility Accessible - Photo 1

King Suite with Tub - Mobility Accessible

This air-conditioned suite is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningRefrigeratorDesk

King Suite With Mobility Accessible Tub

Non-refundable
Breakfast Included
20% OFF$173.89

$139.11

Includes taxes & fees

Guest Reviews

8.6
Excellent977 verified reviews
AI Summary

Guests highly rate the clean and frequently praise the friendly staff.

Categories

Cleanliness8.4
Service8.9
Location8.8
Room Quality8.5
Amenities8.6
Value for Money8.5
Food and Beverage8.6
Overall Experience8.7

Select topics to read reviews

A
AlanusUS
Verified booking
couple
Standard Room
Stayed in Apr 1, 2026

"Exceptional"

10.0
Helpful?
J
JamieusUS
Verified booking
family_with_children
Standard Room
Stayed in Mar 30, 2026

"Exceptional"

10.0

The rooms were spacious, staff was super friendly and helpful when we had a little hiccup with our room and breakfast was great! Lots of great offerings and the coffee was delicious! Super clean facility and very friendly staff.

N/A

Helpful?
L
Love222trav
Verified booking
Couples
Standard Room
Stayed in Mar 27, 2026

"Nice place - clean and friendly staff!"

10.0

This hotel is clean! It is bright! Staff at the front desk are friendly and happy!! What a welcome change from most places these days. The breakfast was good and had many options including sausage, eggs, potatoes, bagels, pancakes, cereal, toast, danish, etc. the breakfast area was also clean! It is easy in and out and free parking. The shower head was fantastic and hot water came quickly with great water pressure. I would definitely go again and the drive to Mayo is not bad at all!

Helpful?
A
AllenusUS
Verified booking
couple
Standard Room
Stayed in Mar 27, 2026

"Exceptional"

10.0
Helpful?
W
WagnerusUS
Verified booking
family_with_children
Standard Room
Stayed in Mar 26, 2026

"Exceptional"

9.0
Helpful?
J
JousUS
Verified booking
couple
Standard Room
Stayed in Mar 24, 2026

"Exceptional"

9.0

Breakfast was good. Beds are very comfortable

Took a while for the hot water to reach 3rd floor

Helpful?
M
MollyusUS
Verified booking
family_with_children
Standard Room
Stayed in Mar 22, 2026

"All in all it was good"

8.0

The breakfast wasn't great.

Helpful?
J
J8987DJjamiep
Verified booking
Family
Standard Room
Stayed in Mar 21, 2026

"Mixed Experiences with Some Concers"

6.0

While the room was spacious, cleanliness was an issue with food splatter on the wall, hot water that took 10 mins plus to warm up and hair in the tub. The biggest disappointment was paying for a Jacuzzi suite we couldn’t use because it was missing parts. Breakfast was minimal. Shuttle service was inconsistent—one driver was very kind, but the return driver was distracted on his phone and driving unsafely.

Helpful?
B
BrentusUS
Verified booking
solo_traveller
Standard Room
Stayed in Mar 21, 2026

"Cleared a refund with the hotel but booking dot Com refused to reimburse"

1.0

Nothing

Everything

Helpful?
J
JamieusUS
Verified booking
solo_traveller
Standard Room
Stayed in Mar 20, 2026

"It was an over good stay, with friendly front desk staff."

8.0

Location to and from the Mayo Clinic.

Nothing besides the hot water. We had to run and wait for hot water everyday for a least 10 mins before we could take a shower.

Helpful?