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8.6 / 10 Guest Rating

Holiday Inn Express Rochester South - Mayo Area by IHG

4141 Maine Avenue SE, Rochester, us

Holiday Inn Express Rochester South - Mayo Area by IHG - main view

About the Property

Spacious Suites with Free WiFi and Shuttle Service
The Comfort Suites Rochester offers spacious suites with free WiFi and flat-screen cable TV. Each suite includes a large work desk, sofa bed, refrigerator, microwave, and coffee maker. A free shuttle to the Rochester Mayo Clinic is available, just 5 miles away.

Indoor Pool, Hot Tub, and Fitness Room
Guests can relax in the indoor pool and hot tub or stay active in the on-site fitness room. The hotel also provides a business center with free WiFi in the lobby for guests' convenience.

Convenient Amenities and Nearby Attractions
Enjoy a daily continental breakfast and a free weekday newspaper during your stay. With Willow Creek Golf Course just 2 miles away, shopping at Apache Mall 4.8 miles away, and easy access to Rochester International Airport, the Comfort Suites Rochester is the perfect choice for your visit.

Facilities & Amenities

WiFi available
Free WiFi
Parking
Free Parking
Non-smoking rooms
Air conditioning
Fitness center
Swimming pool
24-hour front desk
Business center

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Upon check-in, photo identification and credit card is required. All special requests are subject to availability upon check-in. Special requests cannot be guaranteed and may incur additional charges. We are your home away from home, whether traveling for work, pleasure or medical treatment. We offer spacious accommodations and friendly service to all of our guests, as well as special discount rates for patients and family attending the Mayo Clinic. Stay in comfortable guest rooms with premium bedding, a microwave and refrigerator, a work desk and a flat-screen TV. All rooms also have a coffee maker and a USB ports. Guests can start their morning with free hot breakfast and a free weekday newspaper, and enjoy free Wi-Fi anytime. The fitness center and heated indoor pool and hot tub are a great way to relax after a long day. We’re located mere minutes from the Mayo Clinic, so whether you’re visiting the clinic for work or treatment, or visiting a family member or friend, you won't need to commute far. We’re also close to St. Mary’s Hospital and IBM Rochester, as well as Rochester International Airport. Likewise, we have shuttle services to the Mayo Clinic & St. Mary's Hospital. Furthermore, we do not provide Airport Shuttle or local shuttle services to other places. To blow off some steam, hit the nearby Skyline Raceway or head into downtown Rochester for some local dining or shopping. Business travelers will appreciate our business center with a copy and fax machine, and can rent out our meeting rooms for meetings or other events. Laundry and a valet cleaning service are available for guests, as well as a picnic area and on-site coffee shop and sundry shop.Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Suite with Two Queen Beds - Photo 1

Suite with Two Queen Beds

This air-conditioned suite is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 3 beds.

0
Sleeps 6
1 Sofa bed (Variable Size)
2 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

2 Queen Bed Suite

Non-refundable
Breakfast Included
20% OFF$153.66

$122.93

Includes taxes & fees
King Suite - Photo 1

King Suite

This air-conditioned suite is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

King Suite

Non-refundable
Breakfast Included
20% OFF$146.93

$117.54

Includes taxes & fees
Standard King Room with Lake View - Photo 1
Standard King Room with Lake View - Photo 2
Standard King Room with Lake View - Photo 3
Standard King Room with Lake View - Photo 4
Standard King Room with Lake View - Photo 5
Standard King Room with Lake View - Photo 6
Standard King Room with Lake View - Photo 7
Standard King Room with Lake View - Photo 8
Standard King Room with Lake View - Photo 9
Standard King Room with Lake View - Photo 10
1/10

Standard King Room with Lake View

This air-conditioned double room is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

Standard King Room With Lake View

Non-refundable
Breakfast Included
20% OFF$173.89

$139.11

Includes taxes & fees
Standard Room - Photo 1
Standard Room - Photo 2
Standard Room - Photo 3
Standard Room - Photo 4
Standard Room - Photo 5
Standard Room - Photo 6
Standard Room - Photo 7
Standard Room - Photo 8
1/8

Standard Room

Offering free toiletries, this double room includes a private bathroom with a hairdryer. The air-conditioned double room offers a flat-screen TV with cable channels, a tea and coffee maker, a wardrobe, a sofa as well as lake views.

0
Sleeps 2
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

Standard Room

Non-refundable
Breakfast Included
20% OFF$153.66

$122.93

Includes taxes & fees
King Suite with Jetted Tub - Photo 1
King Suite with Jetted Tub - Photo 2
1/2

King Suite with Jetted Tub

This air-conditioned suite includes a flat-screen TV with cable channels and a private bathroom. The unit offers 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningRefrigeratorDesk

King Suite With Jetted Tub

Non-refundable
Breakfast Included
20% OFF$173.89

$139.11

Includes taxes & fees
King Suite with Tub - Mobility Accessible - Photo 1

King Suite with Tub - Mobility Accessible

This air-conditioned suite is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningRefrigeratorDesk

King Suite With Mobility Accessible Tub

Non-refundable
Breakfast Included
20% OFF$173.89

$139.11

Includes taxes & fees

Guest Reviews

8.6
Excellent977 verified reviews
AI Summary

Guests highly rate the clean and frequently praise the friendly staff.

Categories

Cleanliness8.4
Service8.9
Location8.8
Room Quality8.5
Amenities8.6
Value for Money8.5
Food and Beverage8.6
Overall Experience8.7

Select topics to read reviews

M
MikeusUS
Verified booking
couple
Standard Room
Stayed in Mar 2, 2026

"Good"

6.0
Helpful?
G
gaylausUS
Verified booking
couple
Standard Room
Stayed in Feb 26, 2026

"Best breakfast way better than my last stay closer to Mayo staff was excellent"

9.0

Excellent

Helpful?
D
DavidusUS
Verified booking
solo_traveller
Standard Room
Stayed in Feb 24, 2026

"Exceptional"

10.0

Very clean, quiet, and comfortable. Friendly staff.

Helpful?
A
amyusUS
Verified booking
couple
Standard Room
Stayed in Feb 24, 2026

"My stay was nice, but with no water pressure, the shower was terrible"

5.0

Breakfast

the shower, no water pressure at all! The pool was so small

Helpful?
K
KatyG448RIDGEDALE, MISSOURI
Verified booking
Family
Standard Room
Stayed in Jan 25, 2026

"Don’t waste your money"

2.0

The staff is absolutely awful. We stayed two trips in a row so about 2 months apart. The first time we stayed we needed assistance bc air conditioning was not working and we were told “maintenance man was in the pool area”. We went to pool area and saw NO one. We dealt with it and checked out the next day. The following trip was already booked so we just stayed there again (my mistake) and this time the air was not working at all. Went downstairs and believe it or not the lady said “sorry maintenance man is in pool area”. All I could do was laugh and look at her like you’re kidding me. So the maintenance guy has been in the pool for almost 1.5 months lol it’s there way of NOT helping. We checked out and will never be back.

Helpful?
R
RachelusUS
Verified booking
solo_traveller
Standard Room
Stayed in Jan 22, 2026

"Exceptional"

9.0
Helpful?
D
DylanusUS
Verified booking
family_with_children
Standard Room
Stayed in Jan 22, 2026

"Exceptional"

9.0
Helpful?
M
MicheleusUS
Verified booking
extended_group
Standard Room
Stayed in Jan 20, 2026

"Overall it was amazing"

10.0

Enjoy my room staff food pool

We had a wet spot and got locked out

Helpful?
A
AnaisusUS
Verified booking
couple
Standard Room
Stayed in Jan 20, 2026

"Exceptional"

9.0
Helpful?
D
David WusUS
Verified booking
couple
Standard Room
Stayed in Jan 19, 2026

"Exceptional"

9.0

Nice stay

Helpful?