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8.8 / 10 Guest Rating

21c Museum Hotel St Louis

1528 Locust street, Saint Louis, us

21c Museum Hotel St Louis - main view

About the Property

Luxurious Accommodation
Experience the elegance and comfort of 21c Museum Hotel St Louis, offering 4-star rooms with modern amenities including air conditioning, flat-screen TVs, and plush bedding.

Art and Culture
Immerse yourself in art at our hotel, featuring a contemporary art museum within the premises, showcasing thought-provoking exhibitions and installations.

Relaxation and Dining
Unwind by taking a dip in the indoor pool or savor a delicious meal at the on-site restaurant. Enjoy a convenient stay with room service and a 24-hour front desk at your disposal.

Book your stay at 21c Museum Hotel St Louis for a perfect blend of luxury and artistry.

Facilities & Amenities

Fitness facilities
WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
Swimming pool
24-hour front desk
Restaurant

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Loft with Two Queen Beds - Photo 1
Loft with Two Queen Beds - Photo 2
Loft with Two Queen Beds - Photo 3
Loft with Two Queen Beds - Photo 4
1/4

Loft with Two Queen Beds

Offering free toiletries and bathrobes, this suite includes a private bathroom with a bath, a shower and a hairdryer. This suite is air-conditioned and has a flat-screen TV with streaming services, a seating area, a wardrobe and a safe deposit box.

40 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Loft Double Queen

Non-refundable
Room Only
20% OFF$266.4

$213.12

Includes taxes & fees

Loft Double Queen

Non-refundable
Breakfast Included
20% OFF$360.72

$288.58

Includes taxes & fees
Bunk Room - Photo 1
Bunk Room - Photo 2
Bunk Room - Photo 3
Bunk Room - Photo 4
1/4

Bunk Room

Offering free toiletries and bathrobes, this double room includes a private bathroom with a walk-in shower and a hairdryer. The double room offers air conditioning, a seating area, a wardrobe, a safe deposit box, as well as a flat-screen TV with streaming services. The unit has 1 bed.

25 sqm
Sleeps 2
1 Bunk bed (Variable Size)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Bunk Room Non Refundable

Non-refundable
Room Only
20% OFF$264.2

$211.36

Includes taxes & fees

QUADRUPLE LUXURY

Non-refundable
Breakfast Included
20% OFF$356.6

$285.28

Includes taxes & fees
Luxury King Suite - Photo 1
Luxury King Suite - Photo 2
Luxury King Suite - Photo 3
Luxury King Suite - Photo 4
1/4

Luxury King Suite

This spacious suite includes 1 bedroom, a seating area and 1 bathroom with a walk-in shower and a bath. The suite offers air conditioning, a wardrobe, a safe deposit box, heating, as well as a flat-screen TV with streaming services. The unit has 1 bed.

51 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

SUITE LUXURY

Non-refundable
Room Only
20% OFF$573.94

$459.15

Includes taxes & fees

Luxury King Suite

Non-refundable
Breakfast Included
20% OFF$672.15

$537.72

Includes taxes & fees
Deluxe Room, 1 Double Bed, Accessible - Photo 1
Deluxe Room, 1 Double Bed, Accessible - Photo 2
1/2

Deluxe Room, 1 Double Bed, Accessible

1 Double Bed388 sq feet Internet - Free WiFi Entertainment - Flat-screen TV with premium channelsFood & Drink - Espresso maker, room service (limited hours), and free bottled waterSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower, bathrobes, and free toiletriesPractical - Safe, iron/ironing board, and laptop workspaceComfort - Fresh bed sheets (on request), fresh towels (on request), and air conditioningAccessibility - Closed-captioned TVNon-Smoking

36 m2
Sleeps 4
1 Double bed (131-150 cm wide)
Amenities
ShowerSafety deposit boxTelephoneAir conditioningHair dryerBathrobe

DOUBLE Accessible

Non-refundable
Room Only
20% OFF$292.73

$234.18

Includes taxes & fees

DOUBLE Accessible

Non-refundable
Breakfast Included
20% OFF$393.14

$314.51

Includes taxes & fees

Guest Reviews

8.8
Excellent1392 verified reviews
AI Summary

Guests highly rate the friendly staff and frequently praise the unique amenities.

Categories

Cleanliness7.8
Service9.1
Location8.3
Room Quality8.8
Amenities9.3
Value for Money8.8
Food and Beverage9.3
Overall Experience8.8

Select topics to read reviews

K
kaleenausUS
Verified booking
family_with_children
Standard Room
Stayed in Mar 19, 2026

"Good"

3.0

Great location and beautiful

Several mishappens that was probably just our luck. Check in was at four but had to wait almost another full hour for room to be ready. Hot tub was cold, and had to search down for towels because they were never restocked. Server was down entire day so wasn’t able to have any food on sight (main reason we chose this location) Asked for a crib and wasn’t ready with our room and had to wait, not too major but still a pain with a little one.

Helpful?
D
Dbeck726usUS
Verified booking
family_with_children
Standard Room
Stayed in Mar 18, 2026

"Exceptional"

9.0
Helpful?
J
JeffreyusUS
Verified booking
family_with_children
Standard Room
Stayed in Mar 15, 2026

"Very Good"

7.0

Valet parking at $53 is rather expensive. Should be included just like parking just for restaurant located inside hotel . I feel like suite should include parking .

Valet parking should be included

Helpful?
D
DanyellusUS
Verified booking
couple
Standard Room
Stayed in Mar 14, 2026

"Exceptional"

10.0

Loved everything about the hotel. Luxury at AFfordable had a soaking tub and separate shower in our bathroom. Enjoyed our stay.

Helpful?
J
JuliegbGB
Verified booking
family_with_children
Standard Room
Stayed in Mar 9, 2026

"Always stay here when in St Louis fab hotel"

9.0

Everything

Helpful?
C
ClaudeusUS
Verified booking
couple
Standard Room
Stayed in Mar 8, 2026

"Could have been better but I’ll give it another shot. Not bad."

7.0

Beautiful infrastructure

Helpful?
C
CandiceusUS
Verified booking
couple
Standard Room
Stayed in Mar 8, 2026

"Perfect setting if you’re looking for a unique, upscale boutique hotel."

9.0

Beautiful property with something intriguing to look at around every corner. The historic site created the perfect, boutique setting for a weekend getaway for a girls trip.

The room was smaller than expected, but the bathroom was spacious, clean and modern.

Helpful?
L
LeeusUS
Verified booking
couple
Standard Room
Stayed in Mar 3, 2026

"Wonderful vibe filled with kind staff, great location, and lovely amenities! Loved the art! Will go again."

10.0

The friendly people and the artistic vibe as well as being able to get a craft cocktail with out leaving the hotel. The coffee shop was wonderful too! The valet/door lady Rose was a gem! Everyone was very nice and helpful!

It’s a little pricier than some of the other nice, boutique hotels.

Helpful?
A
AnnamarieusUS
Verified booking
solo_traveller
Standard Room
Stayed in Mar 3, 2026

"Exceptional"

10.0
Helpful?
N
NoellausUS
Verified booking
family_with_children
Standard Room
Stayed in Mar 3, 2026

"Exceptional"

10.0

My room was very clean 👌

Coffee

Helpful?
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