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8.6 / 10 Guest Rating

Holiday Inn Express Rochester South - Mayo Area by IHG

4141 Maine Avenue SE, Rochester, us

Holiday Inn Express Rochester South - Mayo Area by IHG - main view

About the Property

Spacious Suites with Free WiFi and Shuttle Service
The Comfort Suites Rochester offers spacious suites with free WiFi and flat-screen cable TV. Each suite includes a large work desk, sofa bed, refrigerator, microwave, and coffee maker. A free shuttle to the Rochester Mayo Clinic is available, just 5 miles away.

Indoor Pool, Hot Tub, and Fitness Room
Guests can relax in the indoor pool and hot tub or stay active in the on-site fitness room. The hotel also provides a business center with free WiFi in the lobby for guests' convenience.

Convenient Amenities and Nearby Attractions
Enjoy a daily continental breakfast and a free weekday newspaper during your stay. With Willow Creek Golf Course just 2 miles away, shopping at Apache Mall 4.8 miles away, and easy access to Rochester International Airport, the Comfort Suites Rochester is the perfect choice for your visit.

Facilities & Amenities

Offsite parking discounted rates available
Fitness facilities (surcharge)
Parking
Non-smoking rooms
Air conditioning
Swimming pool
Family rooms
Lift / Elevator
Luggage storage
Safety deposit box

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Upon check-in, photo identification and credit card is required. All special requests are subject to availability upon check-in. Special requests cannot be guaranteed and may incur additional charges. We are your home away from home, whether traveling for work, pleasure or medical treatment. We offer spacious accommodations and friendly service to all of our guests, as well as special discount rates for patients and family attending the Mayo Clinic. Stay in comfortable guest rooms with premium bedding, a microwave and refrigerator, a work desk and a flat-screen TV. All rooms also have a coffee maker and a USB ports. Guests can start their morning with free hot breakfast and a free weekday newspaper, and enjoy free Wi-Fi anytime. The fitness center and heated indoor pool and hot tub are a great way to relax after a long day. We’re located mere minutes from the Mayo Clinic, so whether you’re visiting the clinic for work or treatment, or visiting a family member or friend, you won't need to commute far. We’re also close to St. Mary’s Hospital and IBM Rochester, as well as Rochester International Airport. Likewise, we have shuttle services to the Mayo Clinic & St. Mary's Hospital. Furthermore, we do not provide Airport Shuttle or local shuttle services to other places. To blow off some steam, hit the nearby Skyline Raceway or head into downtown Rochester for some local dining or shopping. Business travelers will appreciate our business center with a copy and fax machine, and can rent out our meeting rooms for meetings or other events. Laundry and a valet cleaning service are available for guests, as well as a picnic area and on-site coffee shop and sundry shop.Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Suite with Two Queen Beds - Photo 1

Suite with Two Queen Beds

This air-conditioned suite is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 6
2 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

Suite With 2 Queen Beds And Mobility Accessible Tub

Non-refundable
Breakfast Included
20% OFF$179.23

$143.38

Includes taxes & fees
King Suite - Non-Smoking - Photo 1

King Suite - Non-Smoking

This air-conditioned suite is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

1 King Bed Suite

Non-refundable
Breakfast Included
20% OFF$174.68

$139.74

Includes taxes & fees
Standard King Room with Lake View - Photo 1
Standard King Room with Lake View - Photo 2
Standard King Room with Lake View - Photo 3
Standard King Room with Lake View - Photo 4
Standard King Room with Lake View - Photo 5
Standard King Room with Lake View - Photo 6
Standard King Room with Lake View - Photo 7
Standard King Room with Lake View - Photo 8
Standard King Room with Lake View - Photo 9
Standard King Room with Lake View - Photo 10
1/10

Standard King Room with Lake View

This air-conditioned double room is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

Standard King Room With Lake View

Non-refundable
Breakfast Included
20% OFF$199.15

$159.32

Includes taxes & fees
Standard Room - Photo 1
Standard Room - Photo 2
Standard Room - Photo 3
Standard Room - Photo 4
Standard Room - Photo 5
Standard Room - Photo 6
Standard Room - Photo 7
Standard Room - Photo 8
1/8

Standard Room

Offering free toiletries, this double room includes a private bathroom with a hairdryer. The air-conditioned double room offers a flat-screen TV with cable channels, a tea and coffee maker, a wardrobe, a sofa as well as lake views.

0
Sleeps 2
Amenities
Coffee/tea makerTVTelephoneAir conditioningHair dryerRefrigerator

King Suite

Non-refundable
Breakfast Included
20% OFF$172.6

$138.08

Includes taxes & fees
King Suite with Jetted Tub - Photo 1
King Suite with Jetted Tub - Photo 2
1/2

King Suite with Jetted Tub

This air-conditioned suite includes a flat-screen TV with cable channels and a private bathroom. The unit offers 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningRefrigeratorDesk

King Suite With Jetted Tub

Non-refundable
Breakfast Included
20% OFF$199.15

$159.32

Includes taxes & fees
King Suite with Tub - Mobility Accessible - Photo 1

King Suite with Tub - Mobility Accessible

This air-conditioned suite is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 4
1 Extra-large double bed (Super-king size) (181-210 cm wide)
1 Sofa bed (Variable Size)
Amenities
Coffee/tea makerTVTelephoneAir conditioningRefrigeratorDesk

King Suite With Mobility Accessible Tub

Non-refundable
Breakfast Included
20% OFF$199.15

$159.32

Includes taxes & fees
Queen Suite with Tub - Mobility Accessible - Photo 1
Queen Suite with Tub - Mobility Accessible - Photo 2
1/2

Queen Suite with Tub - Mobility Accessible

This air-conditioned suite is consisted of of a flat-screen TV with cable channels and a private bathroom. The unit has 2 beds.

0
Sleeps 6
2 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerTVTelephoneAir conditioningRefrigeratorDesk

Queen Suite with Tub - Mobility Accessible

Non-refundable
Breakfast Included
20% OFF$206.79

$165.43

Includes taxes & fees

Guest Reviews

8.6
Excellent973 verified reviews
AI Summary

Guests highly rate the clean and frequently praise the friendly staff.

Categories

Cleanliness8.4
Service8.9
Location8.8
Room Quality8.5
Amenities8.6
Value for Money8.5
Food and Beverage8.6
Overall Experience8.7

Select topics to read reviews

C
CarrieusUS
Verified booking
family_with_children
Standard Room
Stayed in Jun 17, 2026

"Exceptional"

10.0

This was a quick stay on our way to Yellowstone. This hotel was so clean and the beds were very comfortable. Breakfast was good with several selections.

Helpful?
K
KentusUS
Verified booking
family_with_children
Standard Room
Stayed in Jun 11, 2026

"Family Friendly"

9.0

Great facilities and great breakfast. Holiday Inn Express always has a good family friendly vibe. Rooms are comfortable and clean.

Helpful?
K
KathyusUS
Verified booking
couple
Standard Room
Stayed in Jun 8, 2026

"Exceptional"

9.0
Helpful?
L
LoriusUS
Verified booking
solo_traveller
Standard Room
Stayed in Jun 6, 2026

"Great place to stay"

8.0

Friendly staff, great breakfast!

Water pressure in sink was low, and towels weren't very thick.

Helpful?
T
TammyusUS
Verified booking
solo_traveller
Standard Room
Stayed in Jun 4, 2026

"Exceptional"

9.0

Looked new. Very clean. Breakfast options were varied.

Pool temp was fine but eyes started burning just walking into room. Could not swim nor use hot tub due to chemical excess. Would never allow a child to swim in it. You have less harsh options.

Helpful?
S
SharonusUS
Verified booking
solo_traveller
Standard Room
Stayed in May 31, 2026

"The room was nice however I was not comfortable due to the room being too cold and the issue was not resolved by the sta"

5.0

The location was good and the room was clean.

The temperature in the room could not be controlled. It was too cold in the room and the temperature could not regulated. The staff move me twice to different rooms but it was the same issue in each room.

Helpful?
R
ReyesusUS
Verified booking
solo_traveller
Standard Room
Stayed in May 29, 2026

"Exceptional"

10.0
Helpful?
D
DebusUS
Verified booking
couple
Standard Room
Stayed in May 26, 2026

"Would not stay there again."

3.0

The staff was very nice

It was not clean / we had to get new sheets because there was a big stain on the sheets 🤮. There was hair in the bathtub on the walls and gross things on the wall by the toilet. I had booked another night there but I canceled and booked somewhere else - would not stay there again.

Helpful?
G
GutbrBR
Verified booking
solo_traveller
Standard Room
Stayed in May 22, 2026

"Good"

5.0

The parking lot and the swimming pool.

In the first Room. The air conditioner wasn't working and we found some nails on the floor.. I asked to move to another room and this one was dirty at the sink and had a bad smell....

Helpful?
K
KerryusUS
Verified booking
family_with_children
Standard Room
Stayed in May 15, 2026

"Excellent"

8.0
Helpful?