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8.8 / 10 Guest Rating

21c Museum Hotel St Louis

1528 Locust street, Saint Louis, us

21c Museum Hotel St Louis - main view

About the Property

Luxurious Accommodation
Experience the elegance and comfort of 21c Museum Hotel St Louis, offering 4-star rooms with modern amenities including air conditioning, flat-screen TVs, and plush bedding.

Art and Culture
Immerse yourself in art at our hotel, featuring a contemporary art museum within the premises, showcasing thought-provoking exhibitions and installations.

Relaxation and Dining
Unwind by taking a dip in the indoor pool or savor a delicious meal at the on-site restaurant. Enjoy a convenient stay with room service and a 24-hour front desk at your disposal.

Book your stay at 21c Museum Hotel St Louis for a perfect blend of luxury and artistry.

Facilities & Amenities

Fitness facilities
WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
Swimming pool
24-hour front desk
Restaurant

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Deluxe King Room - Photo 1
Deluxe King Room - Photo 2
Deluxe King Room - Photo 3
Deluxe King Room - Photo 4
1/4

Deluxe King Room

The spacious double room provides air conditioning, a seating area, as well as a private bathroom featuring a walk-in shower and a hairdryer. The unit offers 1 bed.

29 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Deluxe King Spring/Summer 15% Discount

Non-refundable
Room Only
20% OFF$209.58

$167.66

Includes taxes & fees

Deluxe King

Non-refundable
Breakfast Included
20% OFF$293.5

$234.8

Includes taxes & fees
Deluxe King Room - Accessible  - Photo 1
Deluxe King Room - Accessible  - Photo 2
Deluxe King Room - Accessible  - Photo 3
Deluxe King Room - Accessible  - Photo 4
1/4

Deluxe King Room - Accessible

The spacious double room features air conditioning, a seating area, as well as a private bathroom boasting a walk-in shower and a hairdryer. The double room offers a wardrobe, a safe deposit box, heating and a flat-screen TV with streaming services. The unit has 1 bed.

29 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Deluxe King Accessible Spring/Summer 15% Discount

Non-refundable
Room Only
20% OFF$209.58

$167.66

Includes taxes & fees

Deluxe King Accessible

Non-refundable
Breakfast Included
20% OFF$293.5

$234.8

Includes taxes & fees
Luxury Queen Room - Photo 1
Luxury Queen Room - Photo 2
Luxury Queen Room - Photo 3
Luxury Queen Room - Photo 4
Luxury Queen Room - Photo 5
1/5

Luxury Queen Room

Providing free toiletries and bathrobes, this quadruple room includes a private bathroom with a bath, a shower and a hairdryer. The air-conditioned quadruple room provides a flat-screen TV with streaming services, a seating area, a wardrobe and a safe deposit box. The unit offers 2 beds.

39 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Luxury Queen Room

Non-refundable
Room Only
20% OFF$287.28

$229.82

Includes taxes & fees
Loft with Two Queen Beds - Photo 1
Loft with Two Queen Beds - Photo 2
Loft with Two Queen Beds - Photo 3
Loft with Two Queen Beds - Photo 4
1/4

Loft with Two Queen Beds

Offering free toiletries and bathrobes, this suite includes a private bathroom with a bath, a shower and a hairdryer. This suite is air-conditioned and has a flat-screen TV with streaming services, a seating area, a wardrobe and a safe deposit box.

40 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Loft Double Queen Spring/Summer 15% Discount

Non-refundable
Room Only
20% OFF$231.74

$185.39

Includes taxes & fees

Loft Double Queen

Non-refundable
Breakfast Included
20% OFF$319.59

$255.67

Includes taxes & fees
Bunk Room - Photo 1
Bunk Room - Photo 2
Bunk Room - Photo 3
Bunk Room - Photo 4
1/4

Bunk Room

Offering free toiletries and bathrobes, this double room includes a private bathroom with a walk-in shower and a hairdryer. The double room offers air conditioning, a seating area, a wardrobe, a safe deposit box, as well as a flat-screen TV with streaming services. The unit has 1 bed.

25 sqm
Sleeps 2
1 Bunk bed (Variable Size)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

QUADRUPLE LUXURY

Non-refundable
Room Only
20% OFF$258.23

$206.58

Includes taxes & fees

QUADRUPLE LUXURY

Non-refundable
Breakfast Included
20% OFF$317.11

$253.69

Includes taxes & fees
Deluxe Double Queen Room with Roll-In Shower - Photo 1
Deluxe Double Queen Room with Roll-In Shower - Photo 2
Deluxe Double Queen Room with Roll-In Shower - Photo 3
Deluxe Double Queen Room with Roll-In Shower - Photo 4
1/4

Deluxe Double Queen Room with Roll-In Shower

Offering free toiletries and bathrobes, this quadruple room includes a private bathroom with a walk-in shower and a hairdryer. The quadruple room offers air conditioning, a seating area, a wardrobe, a safe deposit box and a flat-screen TV with streaming services. The unit offers 2 beds.

34 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Deluxe Double Queen Room with Roll-In Shower

Non-refundable
Room Only
20% OFF$287.28

$229.82

Includes taxes & fees
Luxury King Suite - Photo 1
Luxury King Suite - Photo 2
Luxury King Suite - Photo 3
Luxury King Suite - Photo 4
1/4

Luxury King Suite

This spacious suite includes 1 bedroom, a seating area and 1 bathroom with a walk-in shower and a bath. The suite offers air conditioning, a wardrobe, a safe deposit box, heating, as well as a flat-screen TV with streaming services. The unit has 1 bed.

51 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

SUITE LUXURY

Non-refundable
Room Only
20% OFF$318.86

$255.09

Includes taxes & fees

Luxury King Suite

Non-refundable
Breakfast Included
20% OFF$392.22

$313.78

Includes taxes & fees
21c King Suite - Photo 1
21c King Suite - Photo 2
21c King Suite - Photo 3
21c King Suite - Photo 4
21c King Suite - Photo 5
1/5

21c King Suite

The fireplace is a top feature of this suite. This spacious suite includes 1 bedroom, a seating area and 1 bathroom with a walk-in shower and a bath. The air-conditioned suite offers a flat-screen TV with streaming services, a wardrobe, a safe deposit box and heating. The unit has 1 bed.

103 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

21c King Suite

Non-refundable
Room Only
20% OFF$907.9

$726.32

Includes taxes & fees
Deluxe Room, 1 Double Bed, Accessible - Photo 1
Deluxe Room, 1 Double Bed, Accessible - Photo 2
1/2

Deluxe Room, 1 Double Bed, Accessible

1 Double Bed388 sq feet Internet - Free WiFi Entertainment - Flat-screen TV with premium channelsFood & Drink - Espresso maker, room service (limited hours), and free bottled waterSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower, bathrobes, and free toiletriesPractical - Safe, iron/ironing board, and laptop workspaceComfort - Fresh bed sheets (on request), fresh towels (on request), and air conditioningAccessibility - Closed-captioned TVNon-Smoking

36 m2
Sleeps 4
1 Double bed (131-150 cm wide)
Amenities
ShowerSafety deposit boxTelephoneAir conditioningHair dryerBathrobe

DOUBLE Accessible

Non-refundable
Room Only
20% OFF$254.83

$203.86

Includes taxes & fees

DOUBLE Accessible

Non-refundable
Breakfast Included
20% OFF$349.45

$279.56

Includes taxes & fees

Guest Reviews

8.8
Excellent1392 verified reviews
AI Summary

Guests highly rate the friendly staff and frequently praise the unique amenities.

Categories

Cleanliness7.8
Service9.1
Location8.3
Room Quality8.8
Amenities9.3
Value for Money8.8
Food and Beverage9.3
Overall Experience8.8

Select topics to read reviews

A
AlexisusUS
Verified booking
couple
Standard Room
Stayed in Jun 3, 2026

"Exceptional"

10.0
Helpful?
C
CORINNEfrFR
Verified booking
solo_traveller
Standard Room
Stayed in Jun 1, 2026

"Moderne et stylé. Personnel très accueillant."

9.0

Moderne et stylé. Personnel très agréable et accueillant.

Rien

Helpful?
M
MossusUS
Verified booking
solo_traveller
Standard Room
Stayed in Jun 1, 2026

"Excellent"

8.0
Helpful?
A
AndreanausUS
Verified booking
solo_traveller
Standard Room
Stayed in May 31, 2026

"Excellent"

8.0
Helpful?
N
NeedrausUS
Verified booking
couple
Standard Room
Stayed in May 30, 2026

"Exceptional"

10.0

I liked everything this place offered. I would like to recommend that you all have something special for birthdays.

Nothing

Helpful?
L
LucasusUS
Verified booking
family_with_children
Standard Room
Stayed in May 29, 2026

"Good"

5.0

Restaurant was closed. Our room was poorly cleaned.

Helpful?
R
RichardusUS
Verified booking
couple
Standard Room
Stayed in May 29, 2026

"Great place to stay near Arch."

10.0

Clean and well run

A little pricey

Helpful?
R
RustinausUS
Verified booking
solo_traveller
Standard Room
Stayed in May 22, 2026

"Very Good"

7.0

It was located close to everything we wanted to do.

The bed and pillows were uncomfortable.

Helpful?
R
RussellusUS
Verified booking
couple
Standard Room
Stayed in May 21, 2026

"Excellent"

8.0
Helpful?
J
JoshuausUS
Verified booking
couple
Standard Room
Stayed in May 19, 2026

"Exceptional"

10.0
Helpful?