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8.8 / 10 Guest Rating

21c Museum Hotel St Louis

1528 Locust street, Saint Louis, us

21c Museum Hotel St Louis - main view

About the Property

Luxurious Accommodation
Experience the elegance and comfort of 21c Museum Hotel St Louis, offering 4-star rooms with modern amenities including air conditioning, flat-screen TVs, and plush bedding.

Art and Culture
Immerse yourself in art at our hotel, featuring a contemporary art museum within the premises, showcasing thought-provoking exhibitions and installations.

Relaxation and Dining
Unwind by taking a dip in the indoor pool or savor a delicious meal at the on-site restaurant. Enjoy a convenient stay with room service and a 24-hour front desk at your disposal.

Book your stay at 21c Museum Hotel St Louis for a perfect blend of luxury and artistry.

Facilities & Amenities

Fitness facilities
WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
Swimming pool
24-hour front desk
Restaurant

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night ยท 2 adults

Available Rooms

Loft with Two Queen Beds - Photo 1
Loft with Two Queen Beds - Photo 2
Loft with Two Queen Beds - Photo 3
Loft with Two Queen Beds - Photo 4
1/4

Loft with Two Queen Beds

Offering free toiletries and bathrobes, this suite includes a private bathroom with a bath, a shower and a hairdryer. This suite is air-conditioned and has a flat-screen TV with streaming services, a seating area, a wardrobe and a safe deposit box.

40 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Loft Double Queen Spring/Summer 15% Discount

Non-refundable
Room Only
20% OFF$221.19

$176.95

Includes taxes & fees

Loft Double Queen

Non-refundable
Breakfast Included
20% OFF$307.31

$245.85

Includes taxes & fees
Bunk Room - Photo 1
Bunk Room - Photo 2
Bunk Room - Photo 3
Bunk Room - Photo 4
1/4

Bunk Room

Offering free toiletries and bathrobes, this double room includes a private bathroom with a walk-in shower and a hairdryer. The double room offers air conditioning, a seating area, a wardrobe, a safe deposit box, as well as a flat-screen TV with streaming services. The unit has 1 bed.

25 sqm
Sleeps 2
1 Bunk bed (Variable Size)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Bunk Room

Non-refundable
Room Only
20% OFF$235.46

$188.37

Includes taxes & fees

Bunk Room

Non-refundable
Breakfast Included
20% OFF$284.11

$227.29

Includes taxes & fees
Luxury King Suite - Photo 1
Luxury King Suite - Photo 2
Luxury King Suite - Photo 3
Luxury King Suite - Photo 4
1/4

Luxury King Suite

This spacious suite includes 1 bedroom, a seating area and 1 bathroom with a walk-in shower and a bath. The suite offers air conditioning, a wardrobe, a safe deposit box, heating, as well as a flat-screen TV with streaming services. The unit has 1 bed.

51 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

SUITE LUXURY

Non-refundable
Room Only
20% OFF$420.55

$336.44

Includes taxes & fees

Luxury King Suite

Non-refundable
Breakfast Included
20% OFF$505.85

$404.68

Includes taxes & fees
Deluxe Room, 1 Double Bed, Accessible - Photo 1
Deluxe Room, 1 Double Bed, Accessible - Photo 2
1/2

Deluxe Room, 1 Double Bed, Accessible

1 Double Bed388 sq feet Internet - Free WiFi Entertainment - Flat-screen TV with premium channelsFood & Drink - Espresso maker, room service (limited hours), and free bottled waterSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower, bathrobes, and free toiletriesPractical - Safe, iron/ironing board, and laptop workspaceComfort - Fresh bed sheets (on request), fresh towels (on request), and air conditioningAccessibility - Closed-captioned TVNon-Smoking

36 m2
Sleeps 4
1 Double bed (131-150 cm wide)
Amenities
ShowerSafety deposit boxTelephoneAir conditioningHair dryerBathrobe

DOUBLE Accessible

Non-refundable
Room Only
20% OFF$241.58

$193.26

Includes taxes & fees

DOUBLE Accessible

Non-refundable
Breakfast Included
20% OFF$333.83

$267.06

Includes taxes & fees

Guest Reviews

8.8
Excellent1392 verified reviews
AI Summary

Guests highly rate the friendly staff and frequently praise the unique amenities.

Categories

Cleanliness7.8
Service9.1
Location8.3
Room Quality8.8
Amenities9.3
Value for Money8.8
Food and Beverage9.3
Overall Experience8.8

Select topics to read reviews

J
JasmineusUS
Verified booking
couple
Standard Room
Stayed in Apr 20, 2026

"Enjoyed my relaxing staycation."

10.0

Love the location , actually felt safe at night .

I didnโ€™t dislike anything about the property

Helpful?
T
TravisusUS
Verified booking
couple
Standard Room
Stayed in Apr 19, 2026

"Good"

5.0
Helpful?
J
JenniferusUS
Verified booking
solo_traveller
Standard Room
Stayed in Apr 18, 2026

"I highly enjoyed the 21C. It was kooky and fun - totally my vibe!"

9.0

I loved the decor, the artwork, the hotel room. It was kooky and fun and I enjoyed it. Bathroom was HUGE and one of my requests was to be on the upper floor and to have the penguin in the room, like on the website. Well, I got the high room, but no penguin. When I went to tell the front desk person, he obliged my request and brought me the big red penguin. :-) Kudos to that guy! He made the stay all the better.

The pillows are feather and they were very hard and uncomfortable. The bed was just ok. The furniture is quite hard/firm but still comfy and fun, I just wish the bed and pillows were better.

Helpful?
M
my383lt4
Verified booking
Family
Standard Room
Stayed in Apr 17, 2026

"Awful. Stay anywhere else."

2.0

Hallways and room felt dirty. Bathroom appears to not be cleaned. Refrigerator was in room but unplugged, phones in room not working and had to call front desk from mobile to have them bring a tv remote to room because there wasnโ€™t one in the room. Most disappointing was valet wrecked my truck, apologized and accepted responsibility on the sidewalk as they pulled my truck up, they filed a claim through PMC their โ€œParking Management Companyโ€ and PMC denied the claim stating โ€œ Our management team conducted a thorough inspection of the property, including the driving path and the vehicle parking area, and we were unable to identify any factors that could have contributed to the damage. There was no damage to any other vehicles or fixed objects that could account for the reported damage.โ€ Would strongly encourage you to stay somewhere else.

Helpful?
4
491marybm
Verified booking
Friends getaway
Standard Room
Stayed in Apr 17, 2026

"Great time"

10.0

Kielan at valet was great. He greeted us and was friendly and informative.

Helpful?
R
RobusUS
Verified booking
solo_traveller
Standard Room
Stayed in Apr 17, 2026

"Lovely"

10.0

Close to Stifel theater. Great restaurants and lovely staff.

No bellhop, something I expect at a hotel of this stature. Room was quite small.

Helpful?
C
CharlesusUS
Verified booking
couple
Standard Room
Stayed in Apr 17, 2026

"Exceptional"

10.0
Helpful?
M
MarissausUS
Verified booking
couple
Standard Room
Stayed in Apr 17, 2026

"Exceptional"

9.0

Decor, Museum and staff were friendly

Decor pillow on the bed was dirty and stained. I also thought the price of the valet parking was beyond expensive.

Helpful?
A
AndrewusUS
Verified booking
family_with_children
Standard Room
Stayed in Apr 17, 2026

"Good"

4.0
Helpful?
J
JabriahusUS
Verified booking
couple
Standard Room
Stayed in Apr 16, 2026

"Exceptional"

10.0
Helpful?