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8.8 / 10 Guest Rating

21c Museum Hotel St Louis

1528 Locust street, Saint Louis, us

21c Museum Hotel St Louis - main view

About the Property

Luxurious Accommodation
Experience the elegance and comfort of 21c Museum Hotel St Louis, offering 4-star rooms with modern amenities including air conditioning, flat-screen TVs, and plush bedding.

Art and Culture
Immerse yourself in art at our hotel, featuring a contemporary art museum within the premises, showcasing thought-provoking exhibitions and installations.

Relaxation and Dining
Unwind by taking a dip in the indoor pool or savor a delicious meal at the on-site restaurant. Enjoy a convenient stay with room service and a 24-hour front desk at your disposal.

Book your stay at 21c Museum Hotel St Louis for a perfect blend of luxury and artistry.

Facilities & Amenities

Fitness facilities
WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
Swimming pool
24-hour front desk
Restaurant

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Loft with Two Queen Beds - Photo 1
Loft with Two Queen Beds - Photo 2
Loft with Two Queen Beds - Photo 3
Loft with Two Queen Beds - Photo 4
1/4

Loft with Two Queen Beds

Offering free toiletries and bathrobes, this suite includes a private bathroom with a bath, a shower and a hairdryer. This suite is air-conditioned and has a flat-screen TV with streaming services, a seating area, a wardrobe and a safe deposit box.

40 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Loft Double Queen

Non-refundable
Room Only
20% OFF$221.84

$177.47

Includes taxes & fees

Loft Double Queen

Non-refundable
Breakfast Included
20% OFF$309.8

$247.84

Includes taxes & fees
Bunk Room - Photo 1
Bunk Room - Photo 2
Bunk Room - Photo 3
Bunk Room - Photo 4
1/4

Bunk Room

Offering free toiletries and bathrobes, this double room includes a private bathroom with a walk-in shower and a hairdryer. The double room offers air conditioning, a seating area, a wardrobe, a safe deposit box, as well as a flat-screen TV with streaming services. The unit has 1 bed.

25 sqm
Sleeps 2
1 Bunk bed (Variable Size)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Bunk Room

Non-refundable
Room Only
20% OFF$239.2

$191.36

Includes taxes & fees

Bunk Room

Non-refundable
Breakfast Included
20% OFF$292.7

$234.16

Includes taxes & fees
Luxury King Suite - Photo 1
Luxury King Suite - Photo 2
Luxury King Suite - Photo 3
Luxury King Suite - Photo 4
1/4

Luxury King Suite

This spacious suite includes 1 bedroom, a seating area and 1 bathroom with a walk-in shower and a bath. The suite offers air conditioning, a wardrobe, a safe deposit box, heating, as well as a flat-screen TV with streaming services. The unit has 1 bed.

51 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Luxury King Suite

Non-refundable
Room Only
20% OFF$472.29

$377.83

Includes taxes & fees

Luxury King Suite

Non-refundable
Breakfast Included
20% OFF$519.7

$415.76

Includes taxes & fees
Deluxe Room, 1 Double Bed, Accessible - Photo 1
Deluxe Room, 1 Double Bed, Accessible - Photo 2
1/2

Deluxe Room, 1 Double Bed, Accessible

1 Double Bed388 sq feet Internet - Free WiFi Entertainment - Flat-screen TV with premium channelsFood & Drink - Espresso maker, room service (limited hours), and free bottled waterSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower, bathrobes, and free toiletriesPractical - Safe, iron/ironing board, and laptop workspaceComfort - Fresh bed sheets (on request), fresh towels (on request), and air conditioningAccessibility - Closed-captioned TVNon-Smoking

36 m2
Sleeps 4
1 Double bed (131-150 cm wide)
Amenities
ShowerSafety deposit boxTelephoneAir conditioningHair dryerBathrobe

DOUBLE Accessible

Non-refundable
Room Only
20% OFF$292.73

$234.18

Includes taxes & fees

DOUBLE Accessible

Non-refundable
Breakfast Included
20% OFF$393.14

$314.51

Includes taxes & fees

Guest Reviews

8.8
Excellent1392 verified reviews
AI Summary

Guests highly rate the friendly staff and frequently praise the unique amenities.

Categories

Cleanliness7.8
Service9.1
Location8.3
Room Quality8.8
Amenities9.3
Value for Money8.8
Food and Beverage9.3
Overall Experience8.8

Select topics to read reviews

J
jacobpF1415UJ
Verified booking
Couples
Standard Room
Stayed in Apr 15, 2026

"Classy Valet Man"

10.0

Kilen is so kind (I'm sorry for the spelling!!) - soon as we got back from dinner, this man saved the day and had an umbrella ready for my lady when she got out of the car in the rain. Thank you again for taking care of us!

Helpful?
R
RachaelusUS
Verified booking
family_with_children
Standard Room
Stayed in Apr 15, 2026

"Exceptional"

10.0
Helpful?
A
AlissausUS
Verified booking
solo_traveller
Standard Room
Stayed in Apr 14, 2026

"Very Good"

7.0
Helpful?
M
MichelleusUS
Verified booking
couple
Standard Room
Stayed in Apr 14, 2026

"Exceptional"

10.0
Helpful?
D
ducknreedsALBUQUERQUE, NEW MEXICO
Verified booking
Friends getaway
Standard Room
Stayed in Apr 13, 2026

"Wonderful experience"

10.0

Visited Hotel 21C to experience their art exhibit. Had an incredible tour with Angie Villa. The hotel is gorgeous, the exhibit was incredible! Ate evening meal in Idol Wolf, with seven other people. Everyone only had great things to say about their meals.

Helpful?
K
KellyusUS
Verified booking
couple
Standard Room
Stayed in Apr 10, 2026

"Horrible experience, would never stay there again."

1.0

The only thing positive was the room was nice once we actually got in the rrom

Check in was supposed to be 4pm. The room was not ready until 7:30. Had dinner reservations that we could not get ready for due to the room not being ready and was told to use the gym locker room which is totally unacceptable when paying that much for a hotel room.

Helpful?
L
LorraineusUS
Verified booking
couple
Standard Room
Stayed in Apr 8, 2026

"Okay. Did not appreciate $50 parking. Room had some faults."

6.0

No views. Pricey for the room I had.

Had to go to main floor for ice, I was on 8th floor. Only one coffee cup. Refrigerator was warm. Couldn't use tub.

Helpful?
M
MichaelausUS
Verified booking
couple
Standard Room
Stayed in Apr 7, 2026

"Concept is great but they currently seem to have some real issues with logistics and infrastructure"

7.0

Great design, well done renovation, love the art, restaurant and bar are good. Housekeeping friendly and helpful.

There are some real infrastructure issues compared to our previous stay. No towels in the gym and pool area, TV remote control out of battery, room phone does not work, broken shower in pool changing room, empty or missing shampoo and body wash in room and gym area showers, only one cup in the room.

Helpful?
E
EmreusUS
Verified booking
extended_group
Standard Room
Stayed in Apr 7, 2026

"WOOOOW"

10.0

WOW

JUST WOW

Helpful?
C
ChristianusUS
Verified booking
couple
Standard Room
Stayed in Apr 6, 2026

"Exceptional"

10.0
Helpful?
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