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8.8 / 10 Guest Rating

21c Museum Hotel St Louis

1528 Locust street, Saint Louis, us

21c Museum Hotel St Louis - main view

About the Property

Luxurious Accommodation
Experience the elegance and comfort of 21c Museum Hotel St Louis, offering 4-star rooms with modern amenities including air conditioning, flat-screen TVs, and plush bedding.

Art and Culture
Immerse yourself in art at our hotel, featuring a contemporary art museum within the premises, showcasing thought-provoking exhibitions and installations.

Relaxation and Dining
Unwind by taking a dip in the indoor pool or savor a delicious meal at the on-site restaurant. Enjoy a convenient stay with room service and a 24-hour front desk at your disposal.

Book your stay at 21c Museum Hotel St Louis for a perfect blend of luxury and artistry.

Facilities & Amenities

Fitness facilities
WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
Swimming pool
24-hour front desk
Restaurant

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night ยท 2 adults

Available Rooms

Deluxe King Room - Accessible  - Photo 1
Deluxe King Room - Accessible  - Photo 2
Deluxe King Room - Accessible  - Photo 3
Deluxe King Room - Accessible  - Photo 4
1/4

Deluxe King Room - Accessible

The spacious double room features air conditioning, a seating area, as well as a private bathroom boasting a walk-in shower and a hairdryer. The double room offers a wardrobe, a safe deposit box, heating and a flat-screen TV with streaming services. The unit has 1 bed.

29 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Deluxe King Accessible

Non-refundable
Room Only
20% OFF$199.54

$159.63

Includes taxes & fees

Deluxe King Accessible

Non-refundable
Breakfast Included
20% OFF$282.2

$225.76

Includes taxes & fees
Loft with Two Queen Beds - Photo 1
Loft with Two Queen Beds - Photo 2
Loft with Two Queen Beds - Photo 3
Loft with Two Queen Beds - Photo 4
1/4

Loft with Two Queen Beds

Offering free toiletries and bathrobes, this suite includes a private bathroom with a bath, a shower and a hairdryer. This suite is air-conditioned and has a flat-screen TV with streaming services, a seating area, a wardrobe and a safe deposit box.

40 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Loft Double Queen

Non-refundable
Room Only
20% OFF$232.99

$186.39

Includes taxes & fees

Loft Double Queen

Non-refundable
Breakfast Included
20% OFF$321.58

$257.26

Includes taxes & fees
Bunk Room - Photo 1
Bunk Room - Photo 2
Bunk Room - Photo 3
Bunk Room - Photo 4
1/4

Bunk Room

Offering free toiletries and bathrobes, this double room includes a private bathroom with a walk-in shower and a hairdryer. The double room offers air conditioning, a seating area, a wardrobe, a safe deposit box, as well as a flat-screen TV with streaming services. The unit has 1 bed.

25 sqm
Sleeps 2
1 Bunk bed (Variable Size)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Bunk Room Non Refundable

Non-refundable
Room Only
20% OFF$194.98

$155.98

Includes taxes & fees

Bunk Room Non Refundable

Non-refundable
Breakfast Included
20% OFF$278.28

$222.62

Includes taxes & fees
Luxury King Suite - Photo 1
Luxury King Suite - Photo 2
Luxury King Suite - Photo 3
Luxury King Suite - Photo 4
1/4

Luxury King Suite

This spacious suite includes 1 bedroom, a seating area and 1 bathroom with a walk-in shower and a bath. The suite offers air conditioning, a wardrobe, a safe deposit box, heating, as well as a flat-screen TV with streaming services. The unit has 1 bed.

51 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Luxury King Suite

Non-refundable
Room Only
20% OFF$329.78

$263.82

Includes taxes & fees

Luxury King Suite

Non-refundable
Breakfast Included
20% OFF$378.46

$302.77

Includes taxes & fees
Deluxe Room, 1 Double Bed, Accessible - Photo 1
Deluxe Room, 1 Double Bed, Accessible - Photo 2
1/2

Deluxe Room, 1 Double Bed, Accessible

1 Double Bed388 sq feet Internet - Free WiFi Entertainment - Flat-screen TV with premium channelsFood & Drink - Espresso maker, room service (limited hours), and free bottled waterSleep - Blackout drapes/curtains and bed sheets Bathroom - Private bathroom, shower, bathrobes, and free toiletriesPractical - Safe, iron/ironing board, and laptop workspaceComfort - Fresh bed sheets (on request), fresh towels (on request), and air conditioningAccessibility - Closed-captioned TVNon-Smoking

36 m2
Sleeps 4
1 Double bed (131-150 cm wide)
Amenities
ShowerSafety deposit boxTelephoneAir conditioningHair dryerBathrobe

DOUBLE Accessible

Non-refundable
Room Only
20% OFF$258.69

$206.95

Includes taxes & fees

DOUBLE Accessible

Non-refundable
Breakfast Included
20% OFF$362.08

$289.66

Includes taxes & fees

Guest Reviews

8.8
Excellent1392 verified reviews
AI Summary

Guests highly rate the friendly staff and frequently praise the unique amenities.

Categories

Cleanliness7.8
Service9.1
Location8.3
Room Quality8.8
Amenities9.3
Value for Money8.8
Food and Beverage9.3
Overall Experience8.8

Select topics to read reviews

W
walnut123
Verified booking
Family
Standard Room
Stayed in May 18, 2026

"The Good, the Bad and the Ugly."

6.0

Stayed here due to a graduation. It was an edict property from Chase travel. Overall the property was nice but except for the museum on the second floor, it has a tired look that needs to be refreshed. Or at least a coat of paint for the hallway on the third floor. Bathroom was dark and spacious but didn't have any makeup accessories like a q-tip. The hotel's restaurant leans to Spanish food. With few restaurants nearby it was crowded. There is no free parking nearby. Parking lots and garages. 21C charges $50 per 24 hours. What was extremely annoying is that you cannot use the Edict hotel credit towards parking. Finally, there is breakfast and lunch at the Good Press. There was always a line for something for breakfast. That is not a hardship, but waiting 34 minutes to receive French Toast is.

Helpful?
C
citimomma
Verified booking
Family
Standard Room
Stayed in May 17, 2026

"Has potential but definitely uneven experience"

8.0

Very well designed rooms and super interesting lobby. Definitely a fun and unexpected location. However the high-end products in the hotel room in the bathroom are always empty and the dispensers do not work, which requires multiple calls to get anything resolved. Restaurants are excellent but thereโ€™s a very long wait for breakfast since everyone has a credit. And do not expect to walk anywhere because there is nothing worth seeing within walking distance so everything will be an Uber from here.

Helpful?
C
CherrieusUS
Verified booking
solo_traveller
Standard Room
Stayed in May 14, 2026

"Exceptional"

10.0
Helpful?
B
BryantusUS
Verified booking
solo_traveller
Standard Room
Stayed in May 14, 2026

"Good"

1.0
Helpful?
T
TravelerGuy802NEW ENGLAND
Verified booking
Business
Standard Room
Stayed in May 13, 2026

"Room for improvement"

6.0

I had business in St Louis so stayed here for a few nights. St Louis could sure use the business as the city has lots of vacant buildings and signs of entrenched poverty. The room was small for the American Midwest, but perfectly fine for 1-2 people. The location is odd. The eerily quiet neighborhood doesn't have much to offer a business traveler. If you're going in/out of the airport, this location is about a .6 mile walk from Union Station, which has a great train to the airport, but .6 miles is far if you have suitcases. If you want to go for a run along riverside, that's about .7 miles from this hotel (kind of far if want to go for a quick run). There are a few restaurants nearby but many of them close at 7 PM or earlier, and don't open at all Monday-Tuesday. The in-hotel restaurant is insanely priced at $50+ for an entree, and I didn't eat there. The hallways have peeling wallpaper and worn carpet, but the condition of my hotel room was better. The very nice in-house fitness center was a reason to pick the hotel, but the AC was broken when I was there and the fitness room was a toasty 78 degrees F, making for a poor experience. The outsourced cleaning staff is clearly overwhelmed; my room wasn't cleaned by 5 PM when I returned from work so I opted out of room cleaning. The lobby is beautiful and art gallery a nice touch, but this hotel doesn't get the basics right.

Helpful?
Y
Yara CristinabrBR
Verified booking
solo_traveller
Standard Room
Stayed in May 11, 2026

"Exceptional"

10.0
Helpful?
R
royceusUS
Verified booking
solo_traveller
Standard Room
Stayed in May 11, 2026

"Will not do it again"

5.0

The bad over took any good there might have been

Room service was the worse

Helpful?
T
ThomusUS
Verified booking
solo_traveller
Standard Room
Stayed in May 8, 2026

"Fun Whimsical and Eclectic"

9.0

The whimsical eccelecticness of the hotel...art work, great bar and restaurant and wonderful health club

Helpful?
A
AlexanderusUS
Verified booking
couple
Standard Room
Stayed in May 5, 2026

"Exceptional"

10.0
Helpful?
J
JohnsonusUS
Verified booking
solo_traveller
Standard Room
Stayed in Apr 30, 2026

"Exceptional"

10.0
Helpful?