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9 / 10 Guest Rating

Residence Inn Rochester Mayo Clinic Area

441 West Center Street, Rochester, us

Residence Inn Rochester Mayo Clinic Area - main view

About the Property

Modern Rooms with Convenient Amenities
The Residence Inn Rochester offers modern rooms with a pull-out sofa bed, pay-per-view, and a cozy fireplace. Guests can enjoy the convenience of a well-equipped kitchen area with a microwave, stove, and dishwasher.

Complimentary Services and Social Events
Enjoy a complimentary breakfast, free grocery assistance service, and laundry/dry cleaning services during your stay. Join in on the regular social events organized by the hotel and make use of the small picnic area for barbecues.

Convenient Location for Shopping and Sightseeing
Located near Apache Mall, Mayowood Mansion, and Miracle Mile Shopping Center, this hotel is the perfect base for exploring Rochester. With attractions just a short drive away, your stay at Residence Inn Rochester Mayo Clinic Area promises both comfort and convenience.

Book your stay now for a memorable Rochester experience at Residence Inn Rochester Mayo Clinic Area!

Facilities & Amenities

WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
24-hour front desk
Business center
Heating
Terrace

Important Information

Check-in & Out

Check-in
Check-out12:00 PM

Property Notes

Upon check-in photo identification and credit card is required. All special requests are subject to availability upon check-in. Special requests cannot be guaranteed and may incur additional charges. Please be advised there is a USD 35 early check-in fee for check-ins before 11:00 AM.Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

One-Bedroom Queen Suite with Sofa Bed and City View - Photo 1
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 2
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 3
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 4
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 5
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 6
1/6

One-Bedroom Queen Suite with Sofa Bed and City View

Providing free toiletries, this double room includes a private bathroom with a shower and a hairdryer. Meals can be prepared in the well-fitted kitchen, which is equipped with a stovetop, a refrigerator, a dishwasher and kitchenware. The spacious air-conditioned double room provides a flat-screen TV with cable channels, a tea and coffee maker, a seating area, a dining area as well as city views. The unit offers 2 beds.

43 sqm
Sleeps 4
1 Sofa bed (Variable Size)
1 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerShowerTVTelephoneAir conditioningHair dryer

One-Bedroom Queen Suite with Sofa Bed and City View

Non-refundable
Breakfast Included
20% OFF$436.55

$349.24

Includes taxes & fees
Studio, 1 Queen Bed with Sofa bed - Photo 1
Studio, 1 Queen Bed with Sofa bed - Photo 2
Studio, 1 Queen Bed with Sofa bed - Photo 3
Studio, 1 Queen Bed with Sofa bed - Photo 4
1/4

Studio, 1 Queen Bed with Sofa bed

1 Queen Bed and 1 Double Sofa BedLayout - Dining area and sitting areaInternet - Free WiFi Entertainment - Premium channels and pay movies Food & Drink - Kitchen with refrigerator, stovetop, microwave, and dishwasherSleep - Premium bedding and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Safe, double sofa bed, and free newspaper; rollaway beds (free) and cribs (free) available on requestComfort - Fresh bed sheets (on request), fresh towels (on request), and climate-controlled air conditioningAccessibility - Low-height door lock, closed-captioned TV, grab bar near toilet, phone accessibility kit, lowered counter and sink height (inches): 34, low-height electrical outlets in bathroom, height-adjustable showerhead, wheelchair accessible, lever door handles, toilet grab bar height (inches): 34, low-height view port in door, roll-in shower width (inches): 31, low-height counter and sink, roll-in shower, wheelchair-width doorways, and wheelchair-accessible doorway width (inches): 32Eco-friendly - Eco-friendly cleaning supplies, energy-saving switches, recycling bin, and LED light bulbsNeed to Know - Housekeeping on requestNon-SmokingRoom is accessed via exterior corridors

Sleeps 4
1 Queen Bed (150-160 cm wide)
1 Sofa bed (131-150 cm wide)
Amenities
Coffee/tea makerSafety deposit boxTelephoneHair dryerRefrigeratorMicrowave

Studio, 1 Queen, Sofa bed

Non-refundable
Breakfast Included
20% OFF$440.39

$352.31

Includes taxes & fees
Suite, 1 Bedroom - Photo 1
Suite, 1 Bedroom - Photo 2
Suite, 1 Bedroom - Photo 3
Suite, 1 Bedroom - Photo 4
Suite, 1 Bedroom - Photo 5
Suite, 1 Bedroom - Photo 6
Suite, 1 Bedroom - Photo 7
Suite, 1 Bedroom - Photo 8
Suite, 1 Bedroom - Photo 9
1/9

Suite, 1 Bedroom

1 Queen Bed and 1 Double Sofa BedLayout - Bedroom, dining area, and sitting areaInternet - Free WiFi Entertainment - Premium channels and pay movies Food & Drink - Kitchen with refrigerator, stovetop, microwave, and dishwasherSleep - Premium bedding and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Safe, double sofa bed, and free newspaper; rollaway beds (free) and cribs (free) available on requestComfort - Fresh bed sheets (on request), fresh towels (on request), and climate-controlled air conditioningAccessibility - Low-height door lock, closed-captioned TV, grab bar near toilet, phone accessibility kit, lowered counter and sink height (inches): 34, low-height electrical outlets in bathroom, height-adjustable showerhead, wheelchair accessible, lever door handles, toilet grab bar height (inches): 34, low-height view port in door, roll-in shower width (inches): 31, low-height counter and sink, roll-in shower, wheelchair-width doorways, and wheelchair-accessible doorway width (inches): 32Eco-friendly - Eco-friendly cleaning supplies, energy-saving switches, recycling bin, and LED light bulbsNeed to Know - Housekeeping on requestNon-SmokingRoom is accessed via exterior corridors

Sleeps 4
1 Queen Bed (150-160 cm wide)
1 Sofa bed (131-150 cm wide)
Amenities
Coffee/tea makerSafety deposit boxTelephoneHair dryerRefrigeratorMicrowave

1 Bedroom Suite, 1 Queen, Sofa bed

Non-refundable
Breakfast Included
20% OFF$473.14

$378.51

Includes taxes & fees

Guest Reviews

9
Exceptional190 verified reviews
AI Summary

Guests highly rate the helpful staff and frequently praise the great breakfast variety.

Categories

Cleanliness9.0
Service9.4
Location9.0
Room Quality8.4
Amenities8.9
Value for Money8.9
Food and Beverage9.5
Overall Experience8.9

Select topics to read reviews

M
MutualFunMICHIGAN
Verified booking
Couples
Standard Room
Stayed in Feb 2, 2026

"Great Stay! Front Desk Danni was very helpful!"

10.0

My husband and I stayed 4 nights during our appointments at Mayo Clinic. This Residence Inn location is so convenient to Mayo/Gondo buildings through their network of "walking subway" corridors to get you to all the Mayo complex in addition to shops and restaurants and to Mayo parking deck. We never had to use the street level which was wonderful! Wheelchairs were accessible at the lower "subway" level at the Residence Inn. To top off our stay was the AMAZING help and friendly service by DANNI at the Front Desk! Danni was outstanding in providing information and helping to coordinate our needs. I even made a point to stop by and thank Dan (Danni's Manager) to acknowledge Danni's great customer service. Great Stay!!

Helpful?
C
cherylfA5137RS
Verified booking
Couples
Standard Room
Stayed in Jan 29, 2026

"Location and guest service"

10.0

Location is great especially during cold months for visits to Mayo Clinic. Walkway to clinic is very convenient leaving our coats in the room. Andrew and Danni go above and beyond to make guests feel welcome. Having appointments during the day, we mainly see Danni in the evenings. Always cheerful, helpful and runs around accommodating to guest needs. Wonderful environment for stressful times!

Helpful?
K
kaumockEXCELSIOR, MINNESOTA
Verified booking
Family
Standard Room
Stayed in Jan 25, 2026

"Very caring staff"

10.0

KAYCE was an amazing receptionist!! So helpful, friendly, caring and kind!

Helpful?
T
Trail11395966364
Verified booking
Couples
Standard Room
Stayed in Jan 21, 2026

"À wonderful experience at the Residence Inn in Rochester…"

10.0

We are staying at the Residence Inn for an extended stay to go to the Mayo Clinic for medical treatment. It is a hallway away from everything we need. What we didn’t expect was how wonderful a difficult experience was made by a kind, caring staff. We get a full delicious breakfast every morning, thanks to Cheryl and Clayton, as well as warmly welcomed everyday by Andrew, Genevieve, Daniel, and many more. Each has treated us a friend and kindnesses above and beyond hotel service have been generously offered. Our room feels like home away from home. We are so thankful.

Helpful?
G
Global29039465595
Verified booking
Family
Standard Room
Stayed in Dec 24, 2025

"Very handy"

10.0

Nice hotel that allows you to access Mayo Clinic buildings without going outside, by walking the subway. Onsite parking garage is handy. Friendly and helpful staff. Enjoyed the free hot and cold breakfast. Cheryl and Clayton were especially helpful. The Maintenance guy was also very quick, helpful, and friendly.

Helpful?
F
F8124YKcarolh
Verified booking
Family
Standard Room
Stayed in Dec 22, 2025

"Great Experience"

10.0

Excellent experience, & staff was exceptional in all areas!! Will stay again! Kelly, front desk personnel, kind, caring, super helpful & always with a smile.

Helpful?
S
S9789KEjudyh
Verified booking
Family
Standard Room
Stayed in Dec 10, 2025

"Great breakfast"

10.0

Best Continental breakfast I've ever had! Great variety! Thank you Cheryl and Clayton for your courtiousness and helpfulness

Helpful?
V
V483GEmelissag
Verified booking
Family
Standard Room
Stayed in Dec 10, 2025

"Breakfast"

10.0

Breakfast was great. Cheryl and Clayton do a fantastic job. Both are very friendly and courteous. They greet and remember us each morning. They make the stay more enjoyable.

Helpful?
D
D7906CIdianep
Verified booking
Family
Standard Room
Stayed in Dec 9, 2025

"Absolutely prefer this place!"

10.0

This is a clean and cordial place! Everyone here is kind and so accommodating, attending to us pleasantly. The evening desk clerk (did not get his name) was very nice and so helpful for local info. The room is very nice., both clean and welcoming. Breakfast was excellently attended to by Cheryl. Such a pleasure to be here!

Helpful?
M
Maps27759629507
Verified booking
Family
Standard Room
Stayed in Dec 9, 2025

"Excellent place to stay!"

10.0

Husband is going through treatment and we booked this hotel/suite. It’s so clean, bright, roomy for wheelchair, cozy and overall perfect. Pricing is fair! Breakfast was hot delicious and Cheryl was on top of the food, cleaning and greeting everyone. The front desk is friendly and very accommodating. Dan, the manager is very sincere and goes out of his way to make you comfortable. Easy access to the SL tunnel to Mayo Clinic. Really, this is the best place to stay if you’re visiting Mayo! You never have to go outside or move your car!!

Helpful?