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9 / 10 Guest Rating

Residence Inn Rochester Mayo Clinic Area

441 West Center Street, Rochester, us

Residence Inn Rochester Mayo Clinic Area - main view

About the Property

Modern Rooms with Convenient Amenities
The Residence Inn Rochester offers modern rooms with a pull-out sofa bed, pay-per-view, and a cozy fireplace. Guests can enjoy the convenience of a well-equipped kitchen area with a microwave, stove, and dishwasher.

Complimentary Services and Social Events
Enjoy a complimentary breakfast, free grocery assistance service, and laundry/dry cleaning services during your stay. Join in on the regular social events organized by the hotel and make use of the small picnic area for barbecues.

Convenient Location for Shopping and Sightseeing
Located near Apache Mall, Mayowood Mansion, and Miracle Mile Shopping Center, this hotel is the perfect base for exploring Rochester. With attractions just a short drive away, your stay at Residence Inn Rochester Mayo Clinic Area promises both comfort and convenience.

Book your stay now for a memorable Rochester experience at Residence Inn Rochester Mayo Clinic Area!

Facilities & Amenities

WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
24-hour front desk
Business center
Heating
Terrace

Important Information

Check-in & Out

Check-in
Check-out12:00 PM

Property Notes

Upon check-in photo identification and credit card is required. All special requests are subject to availability upon check-in. Special requests cannot be guaranteed and may incur additional charges. Please be advised there is a USD 35 early check-in fee for check-ins before 11:00 AM.Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Queen Studio with City View - Photo 1
Queen Studio with City View - Photo 2
Queen Studio with City View - Photo 3
Queen Studio with City View - Photo 4
1/4

Queen Studio with City View

This queen studio offers a cable TV, sitting area with pullout couch and full kitchen.

42 sqm
Sleeps 4
1 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerShowerTVTelephoneAir conditioningHair dryer

Queen Studio with City View

Non-refundable
Breakfast Included
20% OFF$421.44

$337.15

Includes taxes & fees
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 1
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 2
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 3
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 4
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 5
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 6
1/6

One-Bedroom Queen Suite with Sofa Bed and City View

Providing free toiletries, this double room includes a private bathroom with a shower and a hairdryer. Meals can be prepared in the well-fitted kitchen, which is equipped with a stovetop, a refrigerator, a dishwasher and kitchenware. The spacious air-conditioned double room provides a flat-screen TV with cable channels, a tea and coffee maker, a seating area, a dining area as well as city views. The unit offers 2 beds.

43 sqm
Sleeps 4
1 Sofa bed (Variable Size)
1 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerShowerTVTelephoneAir conditioningHair dryer

One-Bedroom Queen Suite with Sofa Bed and City View

Non-refundable
Breakfast Included
20% OFF$451.65

$361.32

Includes taxes & fees
Studio, 1 Queen Bed with Sofa bed - Photo 1
Studio, 1 Queen Bed with Sofa bed - Photo 2
Studio, 1 Queen Bed with Sofa bed - Photo 3
Studio, 1 Queen Bed with Sofa bed - Photo 4
1/4

Studio, 1 Queen Bed with Sofa bed

1 Queen Bed and 1 Double Sofa BedLayout - Dining area and sitting areaInternet - Free WiFi Entertainment - Premium channels and pay movies Food & Drink - Kitchen with refrigerator, stovetop, microwave, and dishwasherSleep - Premium bedding and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Safe, double sofa bed, and free newspaper; rollaway beds (free) and cribs (free) available on requestComfort - Fresh bed sheets (on request), fresh towels (on request), and climate-controlled air conditioningAccessibility - Low-height door lock, closed-captioned TV, grab bar near toilet, phone accessibility kit, lowered counter and sink height (inches): 34, low-height electrical outlets in bathroom, height-adjustable showerhead, wheelchair accessible, lever door handles, toilet grab bar height (inches): 34, low-height view port in door, roll-in shower width (inches): 31, low-height counter and sink, roll-in shower, wheelchair-width doorways, and wheelchair-accessible doorway width (inches): 32Eco-friendly - Eco-friendly cleaning supplies, energy-saving switches, recycling bin, and LED light bulbsNeed to Know - Housekeeping on requestNon-SmokingRoom is accessed via exterior corridors

Sleeps 4
1 Queen Bed (150-160 cm wide)
1 Sofa bed (131-150 cm wide)
Amenities
Coffee/tea makerSafety deposit boxTelephoneHair dryerRefrigeratorMicrowave

Studio, 1 Queen, Sofa bed

Free cancellation
Before Jul 1 (2 days)
Breakfast Included
20% OFF$456.76

$365.41

Includes taxes & fees
Suite, 1 Bedroom - Photo 1
Suite, 1 Bedroom - Photo 2
Suite, 1 Bedroom - Photo 3
Suite, 1 Bedroom - Photo 4
Suite, 1 Bedroom - Photo 5
Suite, 1 Bedroom - Photo 6
Suite, 1 Bedroom - Photo 7
Suite, 1 Bedroom - Photo 8
Suite, 1 Bedroom - Photo 9
1/9

Suite, 1 Bedroom

1 Queen Bed and 1 Double Sofa BedLayout - Bedroom, dining area, and sitting areaInternet - Free WiFi Entertainment - Premium channels and pay movies Food & Drink - Kitchen with refrigerator, stovetop, microwave, and dishwasherSleep - Premium bedding and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Safe, double sofa bed, and free newspaper; rollaway beds (free) and cribs (free) available on requestComfort - Fresh bed sheets (on request), fresh towels (on request), and climate-controlled air conditioningAccessibility - Low-height door lock, closed-captioned TV, grab bar near toilet, phone accessibility kit, lowered counter and sink height (inches): 34, low-height electrical outlets in bathroom, height-adjustable showerhead, wheelchair accessible, lever door handles, toilet grab bar height (inches): 34, low-height view port in door, roll-in shower width (inches): 31, low-height counter and sink, roll-in shower, wheelchair-width doorways, and wheelchair-accessible doorway width (inches): 32Eco-friendly - Eco-friendly cleaning supplies, energy-saving switches, recycling bin, and LED light bulbsNeed to Know - Housekeeping on requestNon-SmokingRoom is accessed via exterior corridors

Sleeps 4
1 Queen Bed (150-160 cm wide)
1 Sofa bed (131-150 cm wide)
Amenities
Coffee/tea makerSafety deposit boxTelephoneHair dryerRefrigeratorMicrowave

1 Bedroom Suite, 1 Queen, Sofa bed

Free cancellation
Before Jul 1 (2 days)
Breakfast Included
20% OFF$489.5

$391.6

Includes taxes & fees

Guest Reviews

9
Exceptional190 verified reviews
AI Summary

Guests highly rate the helpful staff and frequently praise the great breakfast variety.

Categories

Cleanliness9.0
Service9.4
Location9.0
Room Quality8.4
Amenities8.9
Value for Money8.9
Food and Beverage9.5
Overall Experience8.9

Select topics to read reviews

P
P2994PKmikel
Verified booking
Solo travel
Standard Room
Stayed in Nov 26, 2025

"Great staff"

10.0

Cheryl and Clayton are exceptional staff members. Took such good care of me and were so diligent to make my stay was excellent!

Helpful?
3
356sherryl
Verified booking
Family
Standard Room
Stayed in Nov 26, 2025

"Best hotel for Mayo Clinic Visit"

10.0

We wanted to leave a review to share how wonderful our time here was. They have an amazing staff especially Cheryl (the best hotel breakfast cook we have ever had) and Clayton (who helped pack our car for us in the snow!) If you are going to the Mayo Clinic, this is the place to stay!

Helpful?
K
kmurr54EAGAN, MINNESOTA
Verified booking
Family
Standard Room
Stayed in Nov 24, 2025

"Breakfast"

10.0

Cynthia is such a gracious host at breakfast every morning and does a wonderful job with all the food service and making sure that everybody is taken well care of

Helpful?
D
dannyoK4039KJ
Verified booking
Couples
Standard Room
Stayed in Nov 22, 2025

"We treated very well and plan to stay again"

10.0

We have stayed there many times and had great service and the breakfast was great. Dan, Cheryl, Danielle and Zack took very good care of us.

Helpful?
B
boonel240
Verified booking
Family
Standard Room
Stayed in Nov 21, 2025

"Our 2 room suite worked well for our family."

8.0

Very nice. Not quite as handicap friendly as I expected for a hotel full of people using walkers and wheelchairs. Breakfast was tasty each morning and Cheryl made you feel like you were dishing up breakfast in your mom’s kitchen. Friendly staff, clean rooms and close to all things Mayo.

Helpful?
L
L7430LPjeremyk
Verified booking
Family
Standard Room
Stayed in Nov 20, 2025

"Great place to stay with friendly staff."

10.0

Very nice place to stay. Recently been remodeled. Several options for breakfast. Staff in friendly and helpful. We arrive late but check in was no problem. Calvin was working the front desk and was very professional and kind. He explained the parking options we had and how to get around all construction going on downtown. We didn't have any problems during our stay. I plan to stay here again next time I'm in Rochester.

Helpful?
I
I383XMerice
Verified booking
Couples
Standard Room
Stayed in Nov 9, 2025

"Great value and location!"

10.0

Excellent value if you're going to Mayo, right on the subway which makes it a short walk to the main campus. Cheryl is great, she manages the (free) breakfasts. We are making this our go to in Rochester.

Helpful?
7
711elainee
Verified booking
Couples
Standard Room
Stayed in Oct 30, 2025

"Mayo Clinic Hotel"

10.0

Great hotel when we come for care at the Mayo Clinic. The staff are all wonderful and are ready to assist you in any way. Cheryl does a fantastic job in the cantina.

Helpful?
K
K5265YBisabelr
Verified booking
Family
Standard Room
Stayed in Oct 30, 2025

"Great stay!"

10.0

This has been our second time staying at this hotel and both times have been wonderful!! Everyone is always so friendly and knowledgeable! Cheryl always serves a great breakfast!

Helpful?
6
675warrenfDES MOINES, IOWA
Verified booking
Solo travel
Standard Room
Stayed in Oct 30, 2025

"Above and beyond"

10.0

Too make a very long story shorter I will begin with this. The hotel is just a tiny bit dated. The service was great. The food was great. The reason I am writing this is the fact that Kalee went above and beyond. I was hospitalized while staying. I called the front desk told them what was going on and they said they would take care of everything. They did! They even called and said that they had been checking on my vehicle while I was gone for 5 days.

Helpful?