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9 / 10 Guest Rating

Residence Inn Rochester Mayo Clinic Area

441 West Center Street, Rochester, us

Residence Inn Rochester Mayo Clinic Area - main view

About the Property

Modern Rooms with Convenient Amenities
The Residence Inn Rochester offers modern rooms with a pull-out sofa bed, pay-per-view, and a cozy fireplace. Guests can enjoy the convenience of a well-equipped kitchen area with a microwave, stove, and dishwasher.

Complimentary Services and Social Events
Enjoy a complimentary breakfast, free grocery assistance service, and laundry/dry cleaning services during your stay. Join in on the regular social events organized by the hotel and make use of the small picnic area for barbecues.

Convenient Location for Shopping and Sightseeing
Located near Apache Mall, Mayowood Mansion, and Miracle Mile Shopping Center, this hotel is the perfect base for exploring Rochester. With attractions just a short drive away, your stay at Residence Inn Rochester Mayo Clinic Area promises both comfort and convenience.

Book your stay now for a memorable Rochester experience at Residence Inn Rochester Mayo Clinic Area!

Facilities & Amenities

WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
24-hour front desk
Business center
Heating
Terrace

Important Information

Check-in & Out

Check-in
Check-out12:00 PM

Property Notes

Upon check-in photo identification and credit card is required. All special requests are subject to availability upon check-in. Special requests cannot be guaranteed and may incur additional charges. Please be advised there is a USD 35 early check-in fee for check-ins before 11:00 AM.Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Studio, 1 Queen Bed with Sofa bed - Photo 1
Studio, 1 Queen Bed with Sofa bed - Photo 2
Studio, 1 Queen Bed with Sofa bed - Photo 3
Studio, 1 Queen Bed with Sofa bed - Photo 4
1/4

Studio, 1 Queen Bed with Sofa bed

1 Queen Bed and 1 Double Sofa BedLayout - Dining area and sitting areaInternet - Free WiFi Entertainment - Premium channels and pay movies Food & Drink - Kitchen with refrigerator, stovetop, microwave, and dishwasherSleep - Premium bedding and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Safe, double sofa bed, and free newspaper; rollaway beds (free) and cribs (free) available on requestComfort - Fresh bed sheets (on request), fresh towels (on request), and climate-controlled air conditioningAccessibility - Low-height door lock, closed-captioned TV, grab bar near toilet, phone accessibility kit, lowered counter and sink height (inches): 34, low-height electrical outlets in bathroom, height-adjustable showerhead, wheelchair accessible, lever door handles, toilet grab bar height (inches): 34, low-height view port in door, roll-in shower width (inches): 31, low-height counter and sink, roll-in shower, wheelchair-width doorways, and wheelchair-accessible doorway width (inches): 32Eco-friendly - Eco-friendly cleaning supplies, energy-saving switches, recycling bin, and LED light bulbsNeed to Know - Housekeeping on requestNon-SmokingRoom is accessed via exterior corridors

Sleeps 4
1 Queen Bed (150-160 cm wide)
1 Sofa bed (131-150 cm wide)
Amenities
Coffee/tea makerSafety deposit boxTelephoneHair dryerRefrigeratorMicrowave

Studio, 1 Queen, Sofa bed

Non-refundable
Breakfast Included
20% OFF$456.76

$365.41

Includes taxes & fees
Suite, 1 Bedroom - Photo 1
Suite, 1 Bedroom - Photo 2
Suite, 1 Bedroom - Photo 3
Suite, 1 Bedroom - Photo 4
Suite, 1 Bedroom - Photo 5
Suite, 1 Bedroom - Photo 6
Suite, 1 Bedroom - Photo 7
Suite, 1 Bedroom - Photo 8
Suite, 1 Bedroom - Photo 9
1/9

Suite, 1 Bedroom

1 Queen Bed and 1 Double Sofa BedLayout - Bedroom, dining area, and sitting areaInternet - Free WiFi Entertainment - Premium channels and pay movies Food & Drink - Kitchen with refrigerator, stovetop, microwave, and dishwasherSleep - Premium bedding and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Safe, double sofa bed, and free newspaper; rollaway beds (free) and cribs (free) available on requestComfort - Fresh bed sheets (on request), fresh towels (on request), and climate-controlled air conditioningAccessibility - Low-height door lock, closed-captioned TV, grab bar near toilet, phone accessibility kit, lowered counter and sink height (inches): 34, low-height electrical outlets in bathroom, height-adjustable showerhead, wheelchair accessible, lever door handles, toilet grab bar height (inches): 34, low-height view port in door, roll-in shower width (inches): 31, low-height counter and sink, roll-in shower, wheelchair-width doorways, and wheelchair-accessible doorway width (inches): 32Eco-friendly - Eco-friendly cleaning supplies, energy-saving switches, recycling bin, and LED light bulbsNeed to Know - Housekeeping on requestNon-SmokingRoom is accessed via exterior corridors

Sleeps 4
1 Queen Bed (150-160 cm wide)
1 Sofa bed (131-150 cm wide)
Amenities
Coffee/tea makerSafety deposit boxTelephoneHair dryerRefrigeratorMicrowave

1 Bedroom Suite, 1 Queen, Sofa bed

Non-refundable
Breakfast Included
20% OFF$489.5

$391.6

Includes taxes & fees

Guest Reviews

9
Exceptional190 verified reviews
AI Summary

Guests highly rate the helpful staff and frequently praise the great breakfast variety.

Categories

Cleanliness9.0
Service9.4
Location9.0
Room Quality8.4
Amenities8.9
Value for Money8.9
Food and Beverage9.5
Overall Experience8.9

Select topics to read reviews

T
theresasC4543QL
Verified booking
Family
Standard Room
Stayed in Sep 5, 2025

"Boone best IT guy"

10.0

We needed our computer connected to the printer and Boone the IT tech came to our room and within seconds had us connected. He waited until we were able to scan and print with no issues. Great service!

Helpful?
R
reginabI8640WI
Verified booking
Family
Standard Room
Stayed in Sep 2, 2025

"Breakfast"

10.0

Thank you so much, Cheryl. Every day her breakfast was absolutely wonderful – always fresh, full of flavor, and made with such care. Her special omelet was truly amazing, light and fluffy, with such a unique taste that made each morning feel special. Thank you Cheryl!!!

Helpful?
M
M762CVmarkr
Verified booking
Family
Standard Room
Stayed in Aug 20, 2025

"The best hotel near the Mayo Clinic of which I’ve stayed at (3) of the tip rated hotels in the area."

10.0

We particularly enjoy a fresh home made breakfast cooked by Cheryl. We are staying here for 6 weeks and was told there would be a “complimentary continental breakfast”. I heard that and thought, “Oh Boy, not much to eat that’s edible”. What a surprise to find a home style breakfast cooked from scratch by the Chef Cheryl every morning and variations of breakfast daily. I highly recommend the stay at this hotel, clean, friendly and get up and enjoy a great breakfast from Cheryl.

Helpful?
M
marysM6681GC
Verified booking
Family
Standard Room
Stayed in Aug 18, 2025

"Home Away from Home"

10.0

This Residence Inn setting provided everything my husband and I (Jack and Mary) needed for 3.5 weeks. Genoveva our most frequent room cleaner was wonderful. She cleaned our rooms like she was cleaning her own house. Dan, Casey, and Danielle at the desk were helpful many times, with a FAX, copies, and various requests from us. The roof patio on the second floor was such a respite setting after busy days at Mayo Clinic. Breakfasts were very tasty, hot and varied with many options of hot and continental choices accommodating any diet restrictions! And talk about location, with the underground subway level we were never wet on a rainy day. The Food-Co-op 519 1st Ave SW was like a Whole Foods fresh everything, walking distance (with a liquor store behind it). This Residence Inn has it all, we didn't have a car. I highly recommend this hotel.

Helpful?
M
markbA1622NBusUS
Verified booking
Family
Standard Room
Stayed in Aug 9, 2025

"We will never stay anywhere else"

10.0

We will never stay anywhere else in Rochester, ever! The best people work here. Shout out this time to Danny, Kayle, and Andrew. The whole team is A+!

Helpful?
L
lynnbM6537ZJ
Verified booking
Family
Standard Room
Stayed in Aug 2, 2025

"Wonderful RI Mayo"

10.0

Friendly staff. Filly was amazing and helped us settle in. Rooms are clean and very comfortable. The hotel's location is extremely convenient, especially if you are going for appointments at the Mayo Clinic.

Helpful?
X
xiaos329
Verified booking
Couples
Standard Room
Stayed in Jul 30, 2025

"Cozy Stay with Great Updates"

10.0

This was our second time staying here. During our first visit, the hotel was undergoing renovations, but this time everything was complete—and it looks great! The refreshed design and the new outdoor patio are perfect for relaxing and enjoying the summer weather. Filly was incredibly helpful with check-in and gave us great tips about the area. She’s very responsible and truly cares about guests’ safety. We really appreciated her kindness and support!

Helpful?
C
C7032CAmaureenc
Verified booking
Couples
Standard Room
Stayed in Jul 27, 2025

"Never look anywhere else"

10.0

We stay at the Residence Inn/Mayo Clinic area for its convenience but it is much more than that. We have found, each and every time, that desk staff, namely Andrew and Filsan and Cheryl in the kitchen make our stay a 5 star stay every time. It is newly remodeled and they have done a great job on that.

Helpful?
P
peterwT3618PC
Verified booking
Family
Standard Room
Stayed in Jul 26, 2025

"Well run, tunnel to Mayo"

10.0

Kayce the manager treated us like family! We loved her, smile, sass (sense of humor), and service! The facilities are nicely renovated and we appreciated the tunnel to the Mayo main buildings.

Helpful?
H
henrypA174IW
Verified booking
Family
Standard Room
Stayed in Jul 17, 2025

"Kayce,the desk clerk is the BEST!!!!!"

10.0

This motel is the best,The check in Lady Kayce is the most helpful and caring young Lady,she has called to check my health on 2 occasions.If you want a TRULY great experience stay with confidence and let Kayce take care of your needs..THANK YOU Hank&Cathi Pole

Helpful?