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8.8 / 10 Guest Rating

21c Museum Hotel St Louis

1528 Locust street, Saint Louis, us

21c Museum Hotel St Louis - main view

About the Property

Luxurious Accommodation
Experience the elegance and comfort of 21c Museum Hotel St Louis, offering 4-star rooms with modern amenities including air conditioning, flat-screen TVs, and plush bedding.

Art and Culture
Immerse yourself in art at our hotel, featuring a contemporary art museum within the premises, showcasing thought-provoking exhibitions and installations.

Relaxation and Dining
Unwind by taking a dip in the indoor pool or savor a delicious meal at the on-site restaurant. Enjoy a convenient stay with room service and a 24-hour front desk at your disposal.

Book your stay at 21c Museum Hotel St Louis for a perfect blend of luxury and artistry.

Facilities & Amenities

Health or beauty spa nearby
Fitness facilities (surcharge)
Parking
Non-smoking rooms
Air conditioning
Restaurant
Room service
Terrace
Lift / Elevator
Luggage storage

Important Information

Check-in & Out

Check-in
Check-out11:00 AM

Property Notes

Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Deluxe King Room - Accessible - Photo 1
Deluxe King Room - Accessible - Photo 2
Deluxe King Room - Accessible - Photo 3
Deluxe King Room - Accessible - Photo 4
1/4

Deluxe King Room - Accessible

The spacious double room features air conditioning, a seating area, as well as a private bathroom boasting a walk-in shower and a hairdryer. The double room offers a wardrobe, a safe deposit box, heating and a flat-screen TV with streaming services. The unit has 1 bed.

29 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Deluxe King Accessible

Non-refundable
Room Only
20% OFF$230.66

$184.53

Includes taxes & fees

Deluxe King Accessible

Non-refundable
Breakfast Included
20% OFF$319.73

$255.78

Includes taxes & fees
Luxury Queen Room - Photo 1
Luxury Queen Room - Photo 2
Luxury Queen Room - Photo 3
Luxury Queen Room - Photo 4
Luxury Queen Room - Photo 5
1/5

Luxury Queen Room

Providing free toiletries and bathrobes, this quadruple room includes a private bathroom with a bath, a shower and a hairdryer. The air-conditioned quadruple room provides a flat-screen TV with streaming services, a seating area, a wardrobe and a safe deposit box. The unit offers 2 beds.

39 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Luxury Double Queen

Non-refundable
Room Only
20% OFF$263.75

$211

Includes taxes & fees

Luxury Double Queen

Non-refundable
Breakfast Included
20% OFF$358.9

$287.12

Includes taxes & fees
Loft with Two Queen Beds - Photo 1
Loft with Two Queen Beds - Photo 2
Loft with Two Queen Beds - Photo 3
Loft with Two Queen Beds - Photo 4
1/4

Loft with Two Queen Beds

Offering free toiletries and bathrobes, this suite includes a private bathroom with a bath, a shower and a hairdryer. This suite is air-conditioned and has a flat-screen TV with streaming services, a seating area, a wardrobe and a safe deposit box.

40 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Loft Double Queen

Non-refundable
Room Only
20% OFF$274.79

$219.83

Includes taxes & fees

Loft Double Queen

Non-refundable
Breakfast Included
20% OFF$371.94

$297.55

Includes taxes & fees
Deluxe Double Queen Room with Roll-In Shower - Photo 1
Deluxe Double Queen Room with Roll-In Shower - Photo 2
Deluxe Double Queen Room with Roll-In Shower - Photo 3
Deluxe Double Queen Room with Roll-In Shower - Photo 4
1/4

Deluxe Double Queen Room with Roll-In Shower

Offering free toiletries and bathrobes, this quadruple room includes a private bathroom with a walk-in shower and a hairdryer. The quadruple room offers air conditioning, a seating area, a wardrobe, a safe deposit box and a flat-screen TV with streaming services. The unit offers 2 beds.

34 sqm
Sleeps 4
2 Queen bed (151-180 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

Deluxe Double Queen Room with Roll-In Shower

Non-refundable
Room Only
20% OFF$343.7

$274.96

Includes taxes & fees
21c King Suite - Photo 1
21c King Suite - Photo 2
21c King Suite - Photo 3
21c King Suite - Photo 4
21c King Suite - Photo 5
1/5

21c King Suite

The fireplace is a top feature of this suite. This spacious suite includes 1 bedroom, a seating area and 1 bathroom with a walk-in shower and a bath. The air-conditioned suite offers a flat-screen TV with streaming services, a wardrobe, a safe deposit box and heating. The unit has 1 bed.

103 sqm
Sleeps 2
1 Extra-large double bed (Super-king size) (181-210 cm wide)
Amenities
ShowerSafety deposit boxAir conditioningHair dryerBathrobeRefrigerator

21c King Suite

Non-refundable
Room Only
20% OFF$964.31

$771.45

Includes taxes & fees

Guest Reviews

8.8
Excellent1373 verified reviews
AI Summary

Guests highly rate the friendly staff and frequently praise the unique amenities.

Categories

Cleanliness7.8
Service9.1
Location8.3
Room Quality8.8
Amenities9.3
Value for Money8.8
Food and Beverage9.3
Overall Experience8.8

Select topics to read reviews

T
ThomasusUS
Verified booking
solo_traveller
Standard Room
Stayed in Jun 23, 2026

"Excellent"

8.0
Helpful?
A
AliciausUS
Verified booking
couple
Standard Room
Stayed in Jun 22, 2026

"Exceptional"

9.0
Helpful?
H
HeatherusUS
Verified booking
family_with_children
Standard Room
Stayed in Jun 21, 2026

"Excellent"

8.0
Helpful?
M
MarkusUS
Verified booking
couple
Standard Room
Stayed in Jun 17, 2026

"Exceptional"

10.0
Helpful?
K
KimusUS
Verified booking
solo_traveller
Standard Room
Stayed in Jun 11, 2026

"Exceptional"

10.0
Helpful?
L
LindsayusUS
Verified booking
couple
Standard Room
Stayed in Jun 11, 2026

"Exceptional"

10.0
Helpful?
D
DanusUS
Verified booking
couple
Standard Room
Stayed in Jun 11, 2026

"Tremendous value for an epic stay!"

10.0

Excellent museum spaces, great bar and fantastic room.

No parking on site, but the street parking was fine.

Helpful?
R
RandyusUS
Verified booking
couple
Standard Room
Stayed in Jun 9, 2026

"Exceptional"

10.0
Helpful?
L
LorraineusUS
Verified booking
solo_traveller
Standard Room
Stayed in Jun 6, 2026

"Good"

1.0

Nothing. It's in a sketchy part of town, and they charge $50 a day for a fenced-in street lot across the street from the hotel. Or, you take your chances with a street lot a block away from the entrance to the hotel. I canceled my stay since I did not feel safe and the staff were rude.

Stairs to get into the hotel, more stairs to get to the front desk

Helpful?
F
filiatreauusUS
Verified booking
couple
Standard Room
Stayed in Jun 6, 2026

"Exceptional"

10.0
Helpful?
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