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9 / 10 Guest Rating

Residence Inn Rochester Mayo Clinic Area

441 West Center Street, Rochester, us

Residence Inn Rochester Mayo Clinic Area - main view

About the Property

Modern Rooms with Convenient Amenities
The Residence Inn Rochester offers modern rooms with a pull-out sofa bed, pay-per-view, and a cozy fireplace. Guests can enjoy the convenience of a well-equipped kitchen area with a microwave, stove, and dishwasher.

Complimentary Services and Social Events
Enjoy a complimentary breakfast, free grocery assistance service, and laundry/dry cleaning services during your stay. Join in on the regular social events organized by the hotel and make use of the small picnic area for barbecues.

Convenient Location for Shopping and Sightseeing
Located near Apache Mall, Mayowood Mansion, and Miracle Mile Shopping Center, this hotel is the perfect base for exploring Rochester. With attractions just a short drive away, your stay at Residence Inn Rochester Mayo Clinic Area promises both comfort and convenience.

Book your stay now for a memorable Rochester experience at Residence Inn Rochester Mayo Clinic Area!

Facilities & Amenities

WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
24-hour front desk
Business center
Heating
Terrace

Important Information

Check-in & Out

Check-in
Check-out12:00 PM

Property Notes

Upon check-in photo identification and credit card is required. All special requests are subject to availability upon check-in. Special requests cannot be guaranteed and may incur additional charges. Please be advised there is a USD 35 early check-in fee for check-ins before 11:00 AM.Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.

Check Room Availability

1 night · 2 adults

Available Rooms

Queen Studio with City View - Photo 1
Queen Studio with City View - Photo 2
Queen Studio with City View - Photo 3
Queen Studio with City View - Photo 4
1/4

Queen Studio with City View

This queen studio offers a cable TV, sitting area with pullout couch and full kitchen.

42 sqm
Sleeps 4
1 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerShowerTVTelephoneAir conditioningHair dryer

Queen Studio with City View

Non-refundable
Breakfast Included
20% OFF$345.9

$276.72

Includes taxes & fees
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 1
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 2
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 3
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 4
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 5
One-Bedroom Queen Suite with Sofa Bed and City View - Photo 6
1/6

One-Bedroom Queen Suite with Sofa Bed and City View

Providing free toiletries, this double room includes a private bathroom with a shower and a hairdryer. Meals can be prepared in the well-fitted kitchen, which is equipped with a stovetop, a refrigerator, a dishwasher and kitchenware. The spacious air-conditioned double room provides a flat-screen TV with cable channels, a tea and coffee maker, a seating area, a dining area as well as city views. The unit offers 2 beds.

43 sqm
Sleeps 4
1 Sofa bed (Variable Size)
1 Queen bed (151-180 cm wide)
Amenities
Coffee/tea makerShowerTVTelephoneAir conditioningHair dryer

One-Bedroom Queen Suite with Sofa Bed and City View

Non-refundable
Breakfast Included
20% OFF$376.13

$300.9

Includes taxes & fees
Studio, 1 Queen Bed with Sofa bed - Photo 1
Studio, 1 Queen Bed with Sofa bed - Photo 2
Studio, 1 Queen Bed with Sofa bed - Photo 3
Studio, 1 Queen Bed with Sofa bed - Photo 4
1/4

Studio, 1 Queen Bed with Sofa bed

1 Queen Bed and 1 Double Sofa BedLayout - Dining area and sitting areaInternet - Free WiFi Entertainment - Premium channels and pay movies Food & Drink - Kitchen with refrigerator, stovetop, microwave, and dishwasherSleep - Premium bedding and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Safe, double sofa bed, and free newspaper; rollaway beds (free) and cribs (free) available on requestComfort - Fresh bed sheets (on request), fresh towels (on request), and climate-controlled air conditioningAccessibility - Low-height door lock, closed-captioned TV, grab bar near toilet, phone accessibility kit, lowered counter and sink height (inches): 34, low-height electrical outlets in bathroom, height-adjustable showerhead, wheelchair accessible, lever door handles, toilet grab bar height (inches): 34, low-height view port in door, roll-in shower width (inches): 31, low-height counter and sink, roll-in shower, wheelchair-width doorways, and wheelchair-accessible doorway width (inches): 32Eco-friendly - Eco-friendly cleaning supplies, energy-saving switches, recycling bin, and LED light bulbsNeed to Know - Housekeeping on requestNon-SmokingRoom is accessed via exterior corridors

Sleeps 4
1 Queen Bed (150-160 cm wide)
1 Sofa bed (131-150 cm wide)
Amenities
Coffee/tea makerSafety deposit boxTelephoneHair dryerRefrigeratorMicrowave

Studio, 1 Queen, Sofa bed

Free cancellation
Before Jun 28 (2 days)
Breakfast Included
20% OFF$380.68

$304.54

Includes taxes & fees
Suite, 1 Bedroom - Photo 1
Suite, 1 Bedroom - Photo 2
Suite, 1 Bedroom - Photo 3
Suite, 1 Bedroom - Photo 4
Suite, 1 Bedroom - Photo 5
Suite, 1 Bedroom - Photo 6
Suite, 1 Bedroom - Photo 7
Suite, 1 Bedroom - Photo 8
Suite, 1 Bedroom - Photo 9
1/9

Suite, 1 Bedroom

1 Queen Bed and 1 Double Sofa BedLayout - Bedroom, dining area, and sitting areaInternet - Free WiFi Entertainment - Premium channels and pay movies Food & Drink - Kitchen with refrigerator, stovetop, microwave, and dishwasherSleep - Premium bedding and bed sheets Bathroom - Private bathroom, shower/tub combination, free toiletries, and a hair dryerPractical - Safe, double sofa bed, and free newspaper; rollaway beds (free) and cribs (free) available on requestComfort - Fresh bed sheets (on request), fresh towels (on request), and climate-controlled air conditioningAccessibility - Low-height door lock, closed-captioned TV, grab bar near toilet, phone accessibility kit, lowered counter and sink height (inches): 34, low-height electrical outlets in bathroom, height-adjustable showerhead, wheelchair accessible, lever door handles, toilet grab bar height (inches): 34, low-height view port in door, roll-in shower width (inches): 31, low-height counter and sink, roll-in shower, wheelchair-width doorways, and wheelchair-accessible doorway width (inches): 32Eco-friendly - Eco-friendly cleaning supplies, energy-saving switches, recycling bin, and LED light bulbsNeed to Know - Housekeeping on requestNon-SmokingRoom is accessed via exterior corridors

Sleeps 4
1 Queen Bed (150-160 cm wide)
1 Sofa bed (131-150 cm wide)
Amenities
Coffee/tea makerSafety deposit boxTelephoneHair dryerRefrigeratorMicrowave

1 Bedroom Suite, 1 Queen, Sofa bed

Free cancellation
Before Jun 28 (2 days)
Breakfast Included
20% OFF$413.91

$331.13

Includes taxes & fees

Guest Reviews

9
Exceptional190 verified reviews
AI Summary

Guests highly rate the helpful staff and frequently praise the great breakfast variety.

Categories

Cleanliness9.0
Service9.4
Location9.0
Room Quality8.4
Amenities8.9
Value for Money8.9
Food and Beverage9.5
Overall Experience8.9

Select topics to read reviews

E
E8492RPdawnp
Verified booking
Family
Standard Room
Stayed in Jun 2, 2026

"Kelly, the Front Desk person"

8.0

Kelly was amazing. She was professional, friendly and extremely helpful. She did a fabulous job when we needed it most.

Helpful?
M
marksB4736ZP
Verified booking
Family
Standard Room
Stayed in May 18, 2026

"Great desk gal"

10.0

Danni was great and very helpful the traffic down there by the hotel was terrible but Danni was awesome

Helpful?
T
TravelAgentChristinaBOSTON, MASSACHUSETTS
Verified booking
Family
Standard Room
Stayed in May 18, 2026

"Great Family Friendly Choice For Mayo Clinic"

10.0

I am a clinical travel coordinator and I love this property for my Mayo Clinic patient families as they offer a great two bedroom suite category room that is often very well priced. It is connected to the clinic via skyways and management is easy to work with for third party payments and accessible needs.

Helpful?
S
Sunshine18713210960
Verified booking
Solo travel
Standard Room
Stayed in May 4, 2026

"Great place to stay"

10.0

Besides the location, Residence Inn is one of the nicest hotels to stay at in Rochester. Nice variety for breakfast, beautiful balcony view, clean hotel, and friendly staff. Calvin, Danielle, and Dan were awesome and very accommodating. Definitely recommend!

Helpful?
J
jayshreeb2026
Verified booking
Family
Standard Room
Stayed in Apr 30, 2026

"Thanks Danni"

10.0

Danni at the frimt desk was fantastic There was construction and the maps could not get us there. We called fromt desk and Danni stayed on the phone for more thsn 10 minutes to mske sure we reach the hotel. And thrn she was so welcoming even apologizing for the construction that is not in the hotel’s hands

Helpful?
R
Robert F.usUS
Verified booking
couple
Standard Room
Stayed in Apr 21, 2026

"Exceptional"

10.0
Helpful?
D
DayterGREEN BAY, WISCONSIN
Verified booking
Couples
Standard Room
Stayed in Mar 20, 2026

"Great Location for Mayo, But Bed Size Falls Short"

8.0

Stayed at the Residence Inn in Rochester, MN and overall had a really positive experience. The biggest advantage is the direct subway connection to Mayo Clinic—hard to beat that level of convenience, especially during early mornings or bad weather. The rooms are updated, clean, and well-designed for longer stays. Everything felt comfortable and functional, and the overall condition of the hotel is clearly well-maintained. Service was also excellent throughout the stay—staff were friendly, responsive, and made things easy. The only downside, and ultimately the reason I’d hesitate to return, is that all the rooms come with queen-size beds. For a longer stay, especially if you’re used to more space or traveling with a partner, that becomes a noticeable drawback. Overall: great location, great service, solid rooms—but the bed size is a limiting factor.

Helpful?
A
A8245UEdevinb
Verified booking
Solo travel
Standard Room
Stayed in Mar 5, 2026

"Review"

10.0

The experience here was amazing. Great breakfast and room.

Helpful?
6
624marcies
Verified booking
Couples
Standard Room
Stayed in Feb 26, 2026

"Friendly people, convenient location, great rooms"

10.0

My husband was scheduled to be in Rochester for almost 2 months due to a medical procedure at Mayo. Not only were we allowed to go and check out one of the rooms a month prior to our stay, Kelly was so helpful and cheerful in answering all the questions we had prior to coming back. The front desk staff that we dealt with - Kelly, Dani, Dan and Andrew were also so kind and helpful, even when I was constantly coming back down with some odd requests! They were able to provide everything we requested to make our stay even better and as relaxing and stress free as possible. The cleaning staff always did an amazing job on our room! Susana helped us move to a different room without being asked and tried to refuse the tip we wanted to give her for going above and beyond what was expected. My husband ended up in the hospital for 2 weeks, so I spent most of my day there, getting back to the room after 11 pm, which resulted in the dishes getting piled up on the counter because I was too tired to deal with them. I came back to the room one afternoon to find the Florencio loaded all the dirty dishes in the dishwasher and started the dishwasher, which again was above and beyond his normal scope of work. Zach was also so kind and helpful with all my requests - from a squeaky dishwasher door to putting in a hand held shower nozzle so my husband could sit in a shower chair in the tub and take a shower. He said it best when he told me that they know that people don't come to Rochester on vacation, so all the staff does everything they can to make sure that the guests have the very best experience they can, considering everything they are dealing with. He is correct. The guests are dealing with a lot and knowing that the people at the hotel are doing everything they can to make sure the experience is as stress free as possible is all we can ask for. The location of the hotel is as convenient as can be. There are restaurants within walking distance outside, and also through the subway hallways. Getting to the buildings we needed to get to were all easily accessible through the subway hallways. We have to go back within 2 months, and we will definitely be staying at this location again.

Helpful?
T
terricK509LY
Verified booking
Family
Standard Room
Stayed in Feb 18, 2026

"The Perfect Place"

10.0

The perfect home away from home when in Rochester for medical reasons. Housekeeping staff does a fantastic job and is so kind (thank you, Genevieve ) Breakfast includes many choices - always hot and delicious - thank you Cheryl and Clayton! Office staff couldn’t be nicer or more efficient - Dan, Kayce, Dani, Andrew, Kelly. And Zach in charge of maintenance is capable and cheerful. The location is convenient, the accommodations are perfect and the PEOPLE are the whipped cream on top.

Helpful?